trilostane
CHEBI:CHEBI_32260
Definition
An epoxy steroid that is 3,17beta-dihydroxy-5alpha-androst-2-ene-2-carbonitrile in which the oxygen of the epoxy group is joined to the 4alpha and 5 alpha positions.
Chemical Information
- Molecular Formula
- C20H27NO3
- Molecular Mass
- 329.43332
- Charge
- 0
- SMILES
- [H][C@@]12CC[C@@]34O[C@@H]3C(O)=C(C[C@]4(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H])C#N
- InChI
- InChI=1S/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14,20)2/h12-15,17,22-23H,3-9H2,1-2H3/t12-,13-,14-,15-,17+,18-,19+,20+/m0/s1
- InChIKey
- KVJXBPDAXMEYOA-CXANFOAXSA-N
Alternative Names
- 3,17beta-dihydroxy-4alpha,5-epoxy-5alpha-androst-2-ene-2-carbonitrile
- trilostane
- trilostano
- trilostanum
Drug Classification
-
nitrileView Class →
CHEBI:18379
-
3-hydroxy steroidView Class →
CHEBI:36834
-
epoxy steroidView Class →
CHEBI:145217
-
17beta-hydroxy steroidView Class →
CHEBI:35343
-
androstanoidView Class →
CHEBI:50402
-
t186438
-
t186753
-
t187167
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:32260
- DRON_00010000
- 38668
- oboInOwl#hasDbXref
- Wikipedia:Trilostane
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:32260
- active_ingredient_strength
- 1 kg/kg
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect19418
- owl#annotatedSource
- t187001
- owl#someValuesFrom
- t1023230
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 38668
- oboInOwl#hasDbXref
- Wikipedia:Trilostane
- oboInOwl#id
- CHEBI:32260
- listing_expiration_date
- 20251231
- dosage_form
- POWDER
- marketing_start_date
- 20060106
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- Tianjin Pacific Chemical & Pharmaceutical Co., Ltd.
- package_marketing_start_date
- 06-JAN-06
- generic_name
- Trilostane
- active_ingredient_name
- TRILOSTANE
- product_ndc
- 38779-2387
- spl_id
- 6de5801e-ba54-4971-9608-1cd17b6029d4
- package_ndc
- 52128-165-01
- package_description
- 1 kg in 1 CONTAINER (52128-165-01)
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50788
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR