Discuss This Drug

butenafine

CHEBI:CHEBI_3238

Definition

Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.

Chemical Information

Molecular Formula
C23H27N
Molecular Mass
317.46720
Charge
0
SMILES
CN(Cc1ccc(cc1)C(C)(C)C)Cc1cccc2ccccc12
InChI
InChI=1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3
InChIKey
ABJKWBDEJIDSJZ-UHFFFAOYSA-N

Alternative Names

  • (4-tert-Butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amine
  • (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
  • 1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
  • 4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine
  • butenafina
  • butenafine
  • Butenafine
  • butenafinum
  • N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3238
DRON_00010000
47461
oboInOwl#hasDbXref
Wikipedia:Butenafine

Additional References

Wikipedia:Butenafine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:3238
rxcui
1298448
brand_name_suffix
Athletes Foot
package_marketing_start_date
31-DEC-96
upc
0373581000258
active_ingredient_strength
1 kg/kg
manufacturer_name
Albertsons
active_ingredient_name
BUTENAFINE HYDROCHLORIDE
unii
R8XA2029ZI
spl_set_id
e650d8aa-c809-42ee-a1d9-a6321d5364f5
pharm_class
Benzylamines [CS]
package_description
1 TUBE in 1 CARTON (30142-210-02) / 30 g in 1 TUBE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
TOPICAL
marketing_start_date
20020222
spl_id
cc5f372c-2a7c-47f0-b324-d0cf2c363279
package_ndc
73581-210-02
labeler_name
Wal-Mart Stores Inc
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
47461
oboInOwl#hasDbXref
Wikipedia:Butenafine
oboInOwl#hasAlternativeId
CHEBI:205442
oboInOwl#id
CHEBI:3238
marketing_category
BULK INGREDIENT
dosage_form
CREAM
product_type
BULK INGREDIENT
generic_name
Butenafine hydrochloride
brand_name
Butenafine Hydrochloride 1%
brand_name_base
Butenafine Hydrochloride 1%
product_ndc
73581-210
application_number
NDA021307
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_59285
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_12179
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_103610
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect19565
owl#annotatedSource
t187186
owl#someValuesFrom
t549401