Butorphanol
CHEBI:CHEBI_3242
Definition
Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.
Chemical Information
- Molecular Formula
- C21H29NO2
- Molecular Mass
- 327.46050
- Charge
- 0
- SMILES
- Oc1ccc2C[C@H]3N(CC[C@@]4(CCCC[C@@]34O)c2c1)CC1CCC1
- InChI
- InChI=1S/C21H29NO2/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15/h6-7,13,15,19,23-24H,1-5,8-12,14H2/t19-,20+,21-/m1/s1
- InChIKey
- IFKLAQQSCNILHL-QHAWAJNXSA-N
Alternative Names
- (-)-17-(cyclobutylmethyl)morphinan-3,14-diol
- (-)-butorphanol
- (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan
- 17-(cyclobutylmethyl)morphinan-3,14-diol
- butorfanol
- butorphanol
- Butorphanol
- BUTORPHANOL
- butorphanolum
Drug Classification
-
morphinane alkaloidView Class →
CHEBI:25418
-
t185997
-
t186003
-
t186009
-
t186157
-
t186662
-
t186700
-
t186956
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 1841
- oboInOwl#hasDbXref
- Wikipedia:Butorphanol
- core#notation
- CHEBI:3242
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- owl#someValuesFrom
- t476695
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1841
- oboInOwl#hasDbXref
- Wikipedia:Butorphanol
- oboInOwl#hasAlternativeId
- CHEBI:145838
- oboInOwl#id
- CHEBI:3242
- core#notation
- CHEBI:3242
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59282
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00000041
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect19673
- owl#annotatedSource
- t187221