Discuss This Drug

Butorphanol

CHEBI:CHEBI_3242

Definition

Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.

Chemical Information

Molecular Formula
C21H29NO2
Molecular Mass
327.46050
Charge
0
SMILES
Oc1ccc2C[C@H]3N(CC[C@@]4(CCCC[C@@]34O)c2c1)CC1CCC1
InChI
InChI=1S/C21H29NO2/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15/h6-7,13,15,19,23-24H,1-5,8-12,14H2/t19-,20+,21-/m1/s1
InChIKey
IFKLAQQSCNILHL-QHAWAJNXSA-N

Alternative Names

  • (-)-17-(cyclobutylmethyl)morphinan-3,14-diol
  • (-)-butorphanol
  • (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan
  • 17-(cyclobutylmethyl)morphinan-3,14-diol
  • butorfanol
  • butorphanol
  • Butorphanol
  • BUTORPHANOL
  • butorphanolum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3242
DRON_00010000
1841
oboInOwl#hasDbXref
Wikipedia:Butorphanol

Additional References

Wikipedia:Butorphanol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000039
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_55322
owl#someValuesFrom
t476695
core#notation
CHEBI:3242
rxcui
1728355
route
NASAL
dea_schedule
CIV
manufacturer_name
Hospira, Inc.
active_ingredient_strength
100 kg/100kg
package_marketing_start_date
25-FEB-13
pharm_class
Opioid Agonist/Antagonist [EPC]
active_ingredient_name
BUTORPHANOL TARTRATE
package_ndc
47848-005-00
package_description
1 kg in 1 CARTON (47848-005-00)
unii
2L7I72RUHN
spl_set_id
bded5531-8847-4576-9a29-3e44f979d2e0
spl_id
b7be42f0-5b59-4a5a-a667-dfa81ff08b2a
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect19673
owl#annotatedSource
t187221
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1841
oboInOwl#hasDbXref
Wikipedia:Butorphanol
generic_name
Butorphanol Tartrate
oboInOwl#hasAlternativeId
CHEBI:145838
oboInOwl#id
CHEBI:3242
product_type
BULK INGREDIENT
listing_expiration_date
20251231
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SPRAY, METERED
marketing_start_date
20021204
labeler_name
Hospira, Inc.
product_ndc
47848-005
brand_name
Butorphanol Tartrate
brand_name_base
Butorphanol Tartrate
application_number
ANDA078400
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR