Discuss This Drug

cabergoline

CHEBI:CHEBI_3286

Definition

An N-acylurea that is (8R)-ergoline-8-carboxamide in which the hydrogen attached to the piperidine nitrogen (position 6) is substituted by an allyl group and the hydrogens attached to the carboxamide nitrogen are substituted by a 3-(dimethylamino)propyl group and an N-ethylcarbamoyl group. A dopamine D2 receptor agonist, cabergoline is used in the management of Parkinson's disease and of disorders associated with hyperprolactinaemia.

Chemical Information

Molecular Formula
C26H37N5O2
Molecular Mass
451.60430
Charge
0
SMILES
[H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@H](CN2CC=C)C(=O)N(CCCN(C)C)C(=O)NCC
InChI
InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1
InChIKey
KORNTPPJEAJQIU-KJXAQDMKSA-N

Alternative Names

  • (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide
  • (8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide
  • (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
  • 1-((6-allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
  • 1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
  • 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea
  • cabergolina
  • cabergoline
  • Cabergoline
  • cabergolinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3286
DRON_00010000
47579
oboInOwl#hasDbXref
Wikipedia:Cabergoline

Additional References

Wikipedia:Cabergoline

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:3286
rxcui
199703
route
ORAL
active_ingredient_strength
100 kg/100kg
package_marketing_start_date
20211027
manufacturer_name
SOLA Pharmaceuticals, LLC
active_ingredient_name
CABERGOLINE
package_ndc
70069-824-08
package_description
8 TABLET in 1 BOTTLE (70069-824-08)
unii
LL60K9J05T
spl_set_id
e0fb5556-de2c-4822-9960-0700e2907890
nui
N0000175827
pharm_class_epc
Ergot Derivative [EPC]
pharm_class
Ergolines [CS]
pharm_class_cs
Ergolines [CS]
upc
0370069824085
spl_id
3e2ff3e8-fa09-469e-b545-68ab6b168de7
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
47579
oboInOwl#hasDbXref
Wikipedia:Cabergoline
generic_name
CABERGOLINE
brand_name
CABERGOLINE
brand_name_base
CABERGOLINE
oboInOwl#id
CHEBI:3286
product_type
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
POWDER
marketing_category
BULK INGREDIENT
marketing_start_date
20180809
labeler_name
Apicore US LLC
product_ndc
70069-824
application_number
ANDA218109
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_51065
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_5715
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect19770
owl#annotatedSource
t190538
owl#someValuesFrom
t715152