candesartan

CHEBI:CHEBI_3347

Definition

A benzimidazolecarboxylic acid that is 1H-benzimidazole-7-carboxylic acid substituted by an ethoxy group at position 2 and a ({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl) group at position 1. It is a angiotensin receptor antagonist used for the treatment of hypertension.

Chemical Information

Molecular Formula
C24H20N6O3
Molecular Mass
440.45424
Charge
0
SMILES
CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InChI
InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)
InChIKey
HTQMVQVXFRQIKW-UHFFFAOYSA-N

Alternative Names

  • 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylic acid
  • 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid
  • 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
  • 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid
  • Blopress
  • CV-11974

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3347
DRON_00010000
214354
oboInOwl#hasDbXref
Wikipedia:Candesartan

Additional References

Wikipedia:Candesartan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_ndc
17228-0017-9
spl_id
17fffe93-5be4-4184-9724-7dcb478a073e
core#notation
CHEBI:3347
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
214354
oboInOwl#hasDbXref
Wikipedia:Candesartan
oboInOwl#id
CHEBI:3347
generic_name
Candesartan Cilexetil
product_ndc
17228-0017
brand_name
ATACAND
brand_name_base
ATACAND
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_61016
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_149509
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00724207
package_description
50000 TABLET in 1 DRUM (17228-0017-9)
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
POWDER
labeler_name
Mylan Pharmaceuticals Inc.
marketing_start_date
20121204
application_number
ANDA207455
rxcui
578330
active_ingredient_name
CANDESARTAN CILEXETIL
active_ingredient_strength
32 mg/1
unii
R85M2X0D68
nui
M0471776
pharm_class_epc
Thiazide Diuretic [EPC]
pharm_class
Angiotensin 2 Receptor Blocker [EPC]
pharm_class_pe
Increased Diuresis [PE]
pharm_class_cs
Thiazides [CS]
spl_set_id
94a59260-d2b6-464a-b5b9-bbc599e57e10
upc
0362559641302
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
manufacturer_name
Mylan Pharmaceuticals Inc.
package_marketing_start_date
21-MAY-08
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6703
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_149509
owl#someValuesFrom
t994678
owl#annotatedSource
t190495