Captopril
CHEBI:CHEBI_3380
Definition
A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug.
Chemical Information
- Molecular Formula
- C9H15NO3S
- Molecular Mass
- 217.28500
- Charge
- 0
- SMILES
- C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
- InChI
- InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1
- InChIKey
- FAKRSMQSSFJEIM-RQJHMYQMSA-N
Alternative Names
- (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
- 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
- Acepress
- Apopril
- Capoten
- Captolane
- captopril
- captoprilum
- Captopryl
- Captoril
- Cesplon
- CP
- D-2-methyl-3-mercaptopropanoyl-L-proline
- D-3-mercapto-2-methylpropanoyl-L-proline
- Dilabar
- Garranil
- Hypertil
- L-Captopril
- Lopirin
- Tenosbon
- Tensobon
- Tensoprel
Drug Classification
-
N-acylpyrrolidineView Class →
CHEBI:46766
-
L-proline derivativeView Class →
CHEBI:84186
-
alkanethiolView Class →
CHEBI:47908
-
pyrrolidinemonocarboxylic acidView Class →
CHEBI:46701
-
t193159
-
t193387
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:3380
- DRON_00010000
- 1998
- oboInOwl#hasDbXref
- Wikipedia:Captopril
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:3380
- nui
- N0000000181
- pharm_class_epc
- Angiotensin Converting Enzyme Inhibitor [EPC]
- pharm_class
- Angiotensin-converting Enzyme Inhibitors [MoA]
- pharm_class_pe
- Increased Diuresis [PE]
- pharm_class_cs
- Thiazides [CS]
- active_ingredient_strength
- 12.5 mg/1
- pharm_class_moa
- Angiotensin-converting Enzyme Inhibitors [MoA]
- upc
- 0355289344308
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- product_type
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- route
- ORAL
- dosage_form
- POWDER
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- marketing_start_date
- 19900305
- labeler_name
- Changzhou Pharmaceutical Factory
- application_number
- ANDA212809
- spl_id
- b22b5dc6-737e-1ba0-e053-2995a90a09f1
- package_ndc
- 53069-0150-5
- product_ndc
- 16571-830
- rxcui
- 317173
- active_ingredient_name
- CAPTOPRIL
- unii
- 9G64RSX1XD
- manufacturer_name
- AMICI PHARMACEUTICALS LLC
- package_marketing_start_date
- 05-MAR-90
- spl_set_id
- 66604c8e-f6b6-4cf9-9561-f1cb4af0e0d6
- package_description
- 100 TABLET in 1 BOTTLE (0143-1173-01)
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 1998
- oboInOwl#hasDbXref
- Wikipedia:Captopril
- generic_name
- CAPTOPRIL AND HYDROCHLOROTHIAZIDE
- brand_name
- CAPTOPRIL AND HYDROCHLOROTHIAZIDE
- brand_name_base
- CAPTOPRIL AND HYDROCHLOROTHIAZIDE
- oboInOwl#id
- CHEBI:3380
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35457
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00723853
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0110144
- owl#annotatedSource
- t194026
- owl#someValuesFrom
- t906642