dalfampridine
CHEBI:CHEBI_34385
Definition
An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.
Chemical Information
- Molecular Formula
- C5H6N2
- Molecular Mass
- 94.11462
- Charge
- 0
- SMILES
- Nc1ccncc1
- InChI
- InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
- InChIKey
- NUKYPUAOHBNCPY-UHFFFAOYSA-N
Alternative Names
- 4-Aminopyridine
- 4-AP
- 4-Pyridinamine
- 4-Pyridylamine
- Ampyra
- Avitrol
- Dalfampridine
- fampridina
- fampridine
- fampridinum
- gamma-Aminopyridine
- N07XX07
- p-Aminopyridine
- pyridin-4-amine
Treatment Applications
-
critical illness polyneuropathyView Disease →
DOID:14402
-
olivopontocerebellar atrophyView Disease →
DOID:14784
Drug Classification
-
processed material
-
aminopyridineView Class →
CHEBI:38207
-
t193296
-
t193445
-
t193701
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:34385
- DRON_00010000
- 897018
- oboInOwl#hasDbXref
- Wikipedia:Dalfampridine
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:34385
- active_ingredient_strength
- 50 kg/50kg
- active_ingredient_name
- DALFAMPRIDINE
- nui
- N0000175448
- upc
- 0305912533609
- pharm_class_epc
- Potassium Channel Blocker [EPC]
- pharm_class
- Potassium Channel Antagonists [MoA]
- pharm_class_moa
- Potassium Channel Antagonists [MoA]
- spl_set_id
- e10b2d92-2824-4395-8883-6fd52c784aa4
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rxcui
- 897021
- package_marketing_start_date
- 25-FEB-19
- manufacturer_name
- Ascend Laboratories, LLC
- package_description
- 60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (63629-9450-1)
- unii
- BH3B64OKL9
- package_ndc
- 38779-3205-4
- product_type
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- TABLET, FILM COATED, EXTENDED RELEASE
- labeler_name
- Regis Technologies Inc.
- marketing_start_date
- 20110316
- spl_id
- 54a7930d-8690-451e-b3f6-3f27e11ad03e
- application_number
- ANDA208292
- product_ndc
- 71052-645
- oboInOwl#hasOBONamespace
- chebi_ontology
- generic_name
- DALFAMPRIDINE MICRONIZED
- DRON_00010000
- 897018
- oboInOwl#hasDbXref
- Wikipedia:Dalfampridine
- oboInOwl#id
- CHEBI:34385
- brand_name
- DALFAMPRIDINE
- brand_name_base
- DALFAMPRIDINE
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_33289
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0111746
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109304
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_9637
- owl#annotatedSource
- t194025
- owl#someValuesFrom
- t3000597