dalfampridine

CHEBI:CHEBI_34385

Definition

An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.

Chemical Information

Molecular Formula
C5H6N2
Molecular Mass
94.11462
Charge
0
SMILES
Nc1ccncc1
InChI
InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChIKey
NUKYPUAOHBNCPY-UHFFFAOYSA-N

Alternative Names

  • 4-Aminopyridine
  • 4-AP
  • 4-Pyridinamine
  • 4-Pyridylamine
  • Ampyra
  • Avitrol
  • Dalfampridine
  • fampridina
  • fampridine
  • fampridinum
  • gamma-Aminopyridine
  • N07XX07
  • p-Aminopyridine
  • pyridin-4-amine

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:34385
DRON_00010000
897018
oboInOwl#hasDbXref
Wikipedia:Dalfampridine

Additional References

Wikipedia:Dalfampridine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:34385
active_ingredient_strength
50 kg/50kg
active_ingredient_name
DALFAMPRIDINE
nui
N0000175448
upc
0305912533609
pharm_class_epc
Potassium Channel Blocker [EPC]
pharm_class
Potassium Channel Antagonists [MoA]
pharm_class_moa
Potassium Channel Antagonists [MoA]
spl_set_id
e10b2d92-2824-4395-8883-6fd52c784aa4
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
897021
package_marketing_start_date
25-FEB-19
manufacturer_name
Ascend Laboratories, LLC
package_description
60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (63629-9450-1)
unii
BH3B64OKL9
package_ndc
38779-3205-4
product_type
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
TABLET, FILM COATED, EXTENDED RELEASE
labeler_name
Regis Technologies Inc.
marketing_start_date
20110316
spl_id
54a7930d-8690-451e-b3f6-3f27e11ad03e
application_number
ANDA208292
product_ndc
71052-645
oboInOwl#hasOBONamespace
chebi_ontology
generic_name
DALFAMPRIDINE MICRONIZED
DRON_00010000
897018
oboInOwl#hasDbXref
Wikipedia:Dalfampridine
oboInOwl#id
CHEBI:34385
brand_name
DALFAMPRIDINE
brand_name_base
DALFAMPRIDINE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_33289
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_0111746
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_109304
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_9637
owl#annotatedSource
t194025
owl#someValuesFrom
t3000597