Discuss This Drug

Cefotetan

CHEBI:CHEBI_3499

Definition

A semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7alpha, and 7beta positions, respectively, of the cephem skeleton. It is resistant to a wide range of beta-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms.

Chemical Information

Molecular Formula
C17H17N7O8S4
Molecular Mass
575.61900
Charge
0
SMILES
[H][C@]12SCC(CSc3nnnn3C)=C(N1C(=O)[C@]2(NC(=O)C1SC(S1)=C(C(N)=O)C(O)=O)OC)C(O)=O
InChI
InChI=1S/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15-,17+/m1/s1
InChIKey
SRZNHPXWXCNNDU-IXOPCIAXSA-N

Alternative Names

  • (6R,7S)-7-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7S)-7-(4-(carbamoylcarboxymethylene)-1,3-dithiethane-2-carboxamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid
  • 7beta-({[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino)-7alpha-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid
  • cefotetan
  • cefotetan
  • Cefotetan
  • cefotetanum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3499
oboInOwl#hasDbXref
Wikipedia:Cefotetan
DRON_00010000
2187

Additional References

Wikipedia:Cefotetan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:3499
pharm_class_epc
Cephalosporin Antibacterial [EPC]
pharm_class
Cephalosporins [CS]
pharm_class_cs
Cephalosporins [CS]
active_ingredient_strength
2 g/20mL
nui
M0003827
active_ingredient_name
CEFOTETAN
spl_set_id
33b13b93-58ce-44c7-b9a2-af3b3a333f80
upc
0363323386016
unii
0GXP746VXB
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cefotetan
DRON_00010000
2187
generic_name
CEFOTETAN DISODIUM
brand_name
Cefotan
brand_name_base
Cefotan
oboInOwl#id
CHEBI:3499
oboInOwl#hasAlternativeId
CHEBI:558729
rxcui
1743557
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20251231
dosage_form
INJECTION, POWDER, FOR SOLUTION
route
INTRAVENOUS
labeler_name
PAI Holdings, LLC dba PAI Pharma
manufacturer_name
PAI Holdings, LLC dba PAI Pharma
marketing_start_date
20111026
package_marketing_start_date
20111026
product_ndc
0143-9671
spl_id
239c7e32-be35-41ea-b466-2e15d3339398
package_ndc
0143-9671-10
package_description
10 VIAL in 1 CARTON (0143-9671-10) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL (0143-9671-01)
application_number
ANDA091031
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_59358
has_treatment
http://purl.obolibrary.org/obo/DOID_5732
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect21215
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_59358
owl#annotatedSource
t197343
owl#someValuesFrom
t2996971