EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
CHEBI:CHEBI_35664
Definition
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
Alternative Names
- HMG-CoA reductase inhibitor
- HMG-CoA reductase inhibitors
- hydroxymethylglutaryl-CoA reductase inhibitor
- hydroxymethylglutaryl-CoA reductase inhibitors
Drug Classification
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
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- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:HMG-CoA_reductase
- core#notation
- CHEBI:35664
Additional References
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Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:HMG-CoA_reductase
- oboInOwl#id
- CHEBI:35664
- core#notation
- CHEBI:35664
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_87631
- owl#annotatedSource
- t200877
- owl#someValuesFrom
- t313158