Chloroquine
CHEBI:CHEBI_3638
Definition
An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Chemical Information
- Molecular Formula
- C18H26ClN3
- Molecular Mass
- 319.87200
- Charge
- 0
- SMILES
- CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
- InChI
- InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)
- InChIKey
- WHTVZRBIWZFKQO-UHFFFAOYSA-N
Alternative Names
- Aralen
- Artrichin
- Bemaphate
- Capquin
- Chlorochin
- chloroquine
- Chloroquine
- chloroquinum
- cloroquina
- N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
- N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine
- Nivaquine B
- Resoquine
- Reumachlor
- Sanoquin
Treatment Applications
-
Omenn syndromeView Disease →
DOID:0060010
Drug Classification
-
organochlorine compoundView Class →
CHEBI:36683
-
aminoquinolineView Class →
CHEBI:36709
-
secondary amino compoundView Class →
CHEBI:50995
-
tertiary amino compoundView Class →
CHEBI:50996
-
t203156
-
t203167
-
t203548
-
t203943
-
t203984
-
t204112
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 2393
- oboInOwl#hasDbXref
- Wikipedia:Chloroquine
- core#notation
- CHEBI:3638
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- rxcui
- 1117531
- listing_expiration_date
- 20241231
- route
- ORAL
- package_marketing_start_date
- 31-MAY-12
- marketing_start_date
- 20120531
- manufacturer_name
- Avet Pharmaceuticals Inc.
- labeler_name
- AvKARE
- spl_id
- 10c6b637-da34-4640-8988-dfd2eb748186
- package_ndc
- 57451-1116-0
- package_description
- 25 kg in 1 DRUM (57451-1116-0)
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 2393
- oboInOwl#hasDbXref
- Wikipedia:Chloroquine
- oboInOwl#id
- CHEBI:3638
- generic_name
- chloroquine phosphate
- product_type
- BULK INGREDIENT
- dosage_form
- TABLET, COATED
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- brand_name
- Chloroquine Phosphate
- brand_name_base
- Chloroquine Phosphate
- product_ndc
- 57451-1116
- application_number
- ANDA091621
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_88230
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_149484
- core#notation
- CHEBI:3638
- active_ingredient_strength
- 1 kg/kg
- pharm_class
- Antimalarial [EPC]
- active_ingredient_name
- CHLOROQUINE PHOSPHATE
- unii
- 6E17K3343P
- spl_set_id
- ee944d28-f596-4163-a502-e779c0d622bc
- upc
- 0364980177504
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- owl#someValuesFrom
- t1093367
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_101043
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_5801
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect6687
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_149484
- owl#annotatedSource
- t204261
- has_treatment
- http://purl.obolibrary.org/obo/DOID_5230