Chloroquine

CHEBI:CHEBI_3638

Definition

An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Chemical Information

Molecular Formula
C18H26ClN3
Molecular Mass
319.87200
Charge
0
SMILES
CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI
InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)
InChIKey
WHTVZRBIWZFKQO-UHFFFAOYSA-N

Alternative Names

  • Aralen
  • Artrichin
  • Bemaphate
  • Capquin
  • Chlorochin
  • chloroquine
  • Chloroquine
  • chloroquinum
  • cloroquina
  • N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine
  • N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine
  • Nivaquine B
  • Resoquine
  • Reumachlor
  • Sanoquin

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
2393
oboInOwl#hasDbXref
Wikipedia:Chloroquine
core#notation
CHEBI:3638

Additional References

Wikipedia:Chloroquine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
1117531
listing_expiration_date
20241231
route
ORAL
package_marketing_start_date
31-MAY-12
marketing_start_date
20120531
manufacturer_name
Avet Pharmaceuticals Inc.
labeler_name
AvKARE
spl_id
10c6b637-da34-4640-8988-dfd2eb748186
package_ndc
57451-1116-0
package_description
25 kg in 1 DRUM (57451-1116-0)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
2393
oboInOwl#hasDbXref
Wikipedia:Chloroquine
oboInOwl#id
CHEBI:3638
generic_name
chloroquine phosphate
product_type
BULK INGREDIENT
dosage_form
TABLET, COATED
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
brand_name
Chloroquine Phosphate
brand_name_base
Chloroquine Phosphate
product_ndc
57451-1116
application_number
ANDA091621
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_88230
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_149484
core#notation
CHEBI:3638
active_ingredient_strength
1 kg/kg
pharm_class
Antimalarial [EPC]
active_ingredient_name
CHLOROQUINE PHOSPHATE
unii
6E17K3343P
spl_set_id
ee944d28-f596-4163-a502-e779c0d622bc
upc
0364980177504
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#someValuesFrom
t1093367
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_101043
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_5801
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6687
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_149484
owl#annotatedSource
t204261
has_treatment
http://purl.obolibrary.org/obo/DOID_5230