Discuss This Drug

cidofovir anhydrous

CHEBI:CHEBI_3696

Definition

Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

Chemical Information

Molecular Formula
C8H14N3O6P
Molecular Mass
279.18700
Charge
0
SMILES
Nc1ccn(C[C@@H](CO)OCP(O)(O)=O)c(=O)n1
InChI
InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1
InChIKey
VWFCHDSQECPREK-LURJTMIESA-N

Alternative Names

  • cidofovir
  • ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
  • (S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid
  • (S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine
  • (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
  • (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine
  • (S)-HPMPC
  • [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid
  • 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
  • 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine
  • CDV
  • Cidofovir
  • Cidofovir anhydrous

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:3696
oboInOwl#hasDbXref
Wikipedia:Cidofovir

Additional References

Wikipedia:Cidofovir

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:3696
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Cidofovir
oboInOwl#hasAlternativeId
CHEBI:666483
oboInOwl#id
CHEBI:3696
rxcui
199388
product_type
BULK INGREDIENT
listing_expiration_date
20251231
marketing_category
BULK INGREDIENT
dosage_form
INJECTION, SOLUTION
pharm_class
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
route
INTRAVENOUS
marketing_start_date
20190730
active_ingredient_strength
50 g/50g
labeler_name
MAEDA INC
manufacturer_name
Mylan Institutional LLC
package_marketing_start_date
30-JUL-19
generic_name
Cidofovir Anhydrous
active_ingredient_name
CIDOFOVIR
product_ndc
67457-210
spl_id
e7774227-c6ba-439d-a32f-01b67d010fc5
package_ndc
67457-210-05
package_description
1 VIAL, GLASS in 1 CARTON (67457-210-05) / 5 mL in 1 VIAL, GLASS
brand_name
CIDOFOVIR
brand_name_base
CIDOFOVIR
unii
JIL713Q00N
application_number
ANDA201276
spl_set_id
56541229-8c1a-4550-8951-2415ed08e7e9
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_47868
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_530615
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_102532
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_530615
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_59495
owl#someValuesFrom
t252424
owl#annotatedSource
t207620