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Cilazapril

CHEBI:CHEBI_3698

Definition

A pyridazinodiazepine resulting from the formal condensation of the carboxy group of cilazaprilat with ethanol. It is a drug used in the treatment of hypertension and heart failure.

Chemical Information

Molecular Formula
C22H31N3O5
Molecular Mass
417.506
Charge
0
SMILES
C1CC[C@@H](C(N2N1CCC[C@H]2C(=O)O)=O)N[C@H](C(OCC)=O)CCC3=CC=CC=C3
InChI
InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28)/t17-,18-,19-/m0/s1
InChIKey
HHHKFGXWKKUNCY-FHWLQOOXSA-N

Alternative Names

  • (1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
  • cilazapril
  • Cilazapril anhydrous
  • cilazaprilum
  • Dynorm
  • Inhibace
  • Ro 34-2848
  • Vascace
  • Vascase

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
21102
oboInOwl#hasDbXref
Wikipedia:Cilazapril
core#notation
CHEBI:3698

Additional References

Wikipedia:Cilazapril

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
21102
oboInOwl#hasDbXref
Wikipedia:Cilazapril
oboInOwl#id
CHEBI:3698
core#notation
CHEBI:3698
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723853
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_81005
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
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https://w3id.org/def/predibionto#has_drug_108261
owl#annotatedSource
t207696
owl#someValuesFrom
t771744