Discuss This Drug

Clarithromycin

CHEBI:CHEBI_3732

Definition

The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.

Chemical Information

Molecular Formula
C38H69NO13
Molecular Mass
747.95340
Charge
0
SMILES
[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C)OC
InChI
InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChIKey
AGOYDEPGAOXOCK-KCBOHYOISA-N

Alternative Names

  • 6-O-methylerythromycin
  • 6-O-methylerythromycin A
  • CLA
  • clarithromycin
  • Clarithromycin
  • CLARITHROMYCIN
  • clarithromycina
  • clarithromycine
  • clarithromycinum
  • O(6)-methylerythromycin

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
21212
oboInOwl#hasDbXref
Reaxys:3581974
core#notation
CHEBI:3732

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
60 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (0527-1930-06)
package_ndc
0781-6022-52
active_ingredient_name
CLARITHROMYCIN
rxcui
359385
active_ingredient_strength
125 mg/5mL
nui
M0028311
unii
H1250JIK0A
spl_set_id
71a836d0-d60f-6418-e053-2a95a90aa6ef
upc
0305271930064
manufacturer_name
Direct_Rx
product_type
BULK INGREDIENT
dosage_form
FOR SUSPENSION
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
Teva API India Ltd
marketing_start_date
20070820
application_number
ANDA065384
product_ndc
38779-1937
package_marketing_start_date
04-SEP-07
listing_expiration_date
20241231
route
ORAL
spl_id
05ef280b-60a9-77ec-e063-6394a90a7821
has_treatment
http://purl.obolibrary.org/obo/DOID_4131
Antibiotic_Name
http://purl.obolibrary.org/obo/DOID_0040083
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113496
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect22453
owl#annotatedSource
t207688
owl#someValuesFrom
t2999747
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
21212
oboInOwl#hasDbXref
Reaxys:3581974
oboInOwl#id
CHEBI:3732
oboInOwl#hasAlternativeId
CHEBI:670147
generic_name
CLARITHROMYCIN
brand_name
CLARITHROMYCIN
brand_name_base
CLARITHROMYCIN
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_48001
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:3732
pharm_class_moa
Cytochrome P450 3A Inhibitors [MoA]
pharm_class
Cytochrome P450 3A Inhibitors [MoA]
pharm_class_epc
Macrolide Antimicrobial [EPC]
pharm_class_cs
Macrolides [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class