Clonazepam

CHEBI:CHEBI_3756

Definition

1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.

Chemical Information

Molecular Formula
C15H10ClN3O3
Molecular Mass
315.71100
Charge
0
SMILES
[O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1
InChI
InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)
InChIKey
DGBIGWXXNGSACT-UHFFFAOYSA-N

Alternative Names

  • 1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one
  • 5-(2-Chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one
  • 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  • 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
  • 5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  • clonazepam
  • CLONAZEPAM
  • clonazepamum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Clonazepam
DRON_00010000
2598
core#notation
CHEBI:3756

Additional References

Wikipedia:Clonazepam

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
TABLET, ORALLY DISINTEGRATING
labeler_name
REMEDYREPACK INC.
application_number
ANDA074869
product_ndc
70518-3849
listing_expiration_date
20241231
marketing_start_date
19960308
spl_id
fafdf6e5-7b28-4cff-83ae-0a65450a8554
package_ndc
71335-1843-1
package_marketing_start_date
11-MAY-21
package_description
60 TABLET in 1 BOTTLE, PLASTIC (71610-039-53)
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Clonazepam
DRON_00010000
2598
oboInOwl#hasAlternativeId
CHEBI:102465
oboInOwl#id
CHEBI:3756
generic_name
CLONAZEPAM
brand_name
Klonopin
brand_name_base
Klonopin
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35623
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00000072
has_treatment
http://purl.obolibrary.org/obo/DOID_12859
route
ORAL
core#notation
CHEBI:3756
active_ingredient_name
CLONAZEPAM
dea_schedule
CIV
active_ingredient_strength
1 kg/kg
nui
M0002356
pharm_class_epc
Benzodiazepine [EPC]
pharm_class
Benzodiazepines [CS]
pharm_class_cs
Benzodiazepines [CS]
upc
0372789315300
spl_set_id
f613573a-3e8b-4abf-af69-0268f3d6f481
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
rxcui
349198
manufacturer_name
REMEDYREPACK INC.
unii
5PE9FDE8GB
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect22712
owl#annotatedSource
t207630
owl#someValuesFrom
t3000462