Atazanavir
CHEBI:CHEBI_37924
Definition
A heavily substituted carbohydrazide that is an antiretroviral drug of the protease inhibitor (PI) class used to treat infection of human immunodeficiency virus (HIV).
Chemical Information
- Molecular Formula
- C38H52N6O7
- Molecular Mass
- 704.85550
- Charge
- 0
- SMILES
- COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(cc1)-c1ccccn1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C
- InChI
- InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
- InChIKey
- AXRYRYVKAWYZBR-GASGPIRDSA-N
Alternative Names
- atazanavir
- atazanavirum
- ATZ
- dimethyl (3S,8S,9S,12S)-9-benzyl-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-6-[4-(2-pyridyl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate
Treatment Applications
Drug Classification
-
carbohydrazideView Class →
CHEBI:35363
-
t206900
-
t207358
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Atazanavir
- DRON_00010000
- 343047
- core#notation
- CHEBI:37924
Additional References
Wikipedia:Atazanavir
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Atazanavir
- DRON_00010000
- 343047
- generic_name
- atazanavir and cobicistat
- brand_name
- EVOTAZ
- brand_name_base
- EVOTAZ
- oboInOwl#id
- CHEBI:37924
- product_type
- BULK INGREDIENT
- marketing_category
- EXPORT ONLY
- dosage_form
- CAPSULE, GELATIN COATED
- product_ndc
- 65015-678
- application_number
- NDA206353
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35660
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_start_date
- 20150129
- labeler_name
- Zydus Pharmaceuticals USA Inc.
- spl_id
- 7e699ffb-f6bd-4e26-8c38-869f41cf7b56
- package_ndc
- 65015-678-61
- package_description
- 100 kg in 1 DRUM (65015-678-61)
- core#notation
- CHEBI:37924
- pharm_class
- P-Glycoprotein Inhibitors [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rxcui
- 1601660
- active_ingredient_strength
- 50 mg/kg
- pharm_class_moa
- Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA]
- nui
- N0000190108
- package_marketing_start_date
- 11-JUN-18
- manufacturer_name
- Zydus Pharmaceuticals USA Inc.
- active_ingredient_name
- COBICISTAT
- unii
- 4MT4VIE29P
- pharm_class_epc
- Cytochrome P450 3A Inhibitor [EPC]
- spl_set_id
- 83db29d7-5d85-49d6-8cb6-740473365cf8
- upc
- 0370710105235
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_111129
- owl#annotatedSource
- t207594
- owl#someValuesFrom
- t3000922