Discuss This Drug

rosuvastatin

CHEBI:CHEBI_38545

Definition

A dihydroxy monocarboxylic acid that is (6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl} hept-6-enoic acid carrying two hydroxy substituents at positions 3 and 5 (the 3R,5S-diastereomer).

Chemical Information

Molecular Formula
C22H28FN3O6S
Molecular Mass
481.53800
Charge
0
SMILES
CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O
InChI
InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
InChIKey
BPRHUIZQVSMCRT-VEUZHWNKSA-N

Alternative Names

  • (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
  • (3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
  • (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid
  • rosuvastatin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
301542
oboInOwl#hasDbXref
Wikipedia:Rosuvastatin
core#notation
CHEBI:38545

Additional References

Wikipedia:Rosuvastatin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
82009-019
marketing_start_date
20030812
labeler_name
Amoli Organics (A Division of Umedica Laboratories Pvt.Ltd.)
package_ndc
0904-6780-61
listing_expiration_date
20241231
spl_id
253b36ff-f814-bfdd-e063-6294a90a5c07
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
301542
oboInOwl#hasDbXref
Wikipedia:Rosuvastatin
oboInOwl#id
CHEBI:38545
generic_name
Rosuvastatin Calcium (Process II)
brand_name
Crestor
brand_name_base
Crestor
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_67079
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_38363
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_77313
route
ORAL
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
TABLET, COATED
application_number
ANDA079166
package_description
30 TABLET, FILM COATED in 1 BOTTLE (71335-1741-1)
package_marketing_start_date
20170106
rxcui
2167575
manufacturer_name
Biocon Pharma Inc
has_treatment
http://purl.obolibrary.org/obo/DOID_3145
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23116
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_77313
owl#annotatedSource
t211081
owl#someValuesFrom
t3775958
core#notation
CHEBI:38545
pharm_class_epc
HMG-CoA Reductase Inhibitor [EPC]
pharm_class
Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]
pharm_class_moa
Hydroxymethylglutaryl-CoA Reductase Inhibitors [MoA]
upc
0347335984835
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
active_ingredient_strength
50 kg/50kg
nui
N0000000121
active_ingredient_name
ROSUVASTATIN
spl_set_id
f77e97f3-aaed-0cd5-e053-6294a90aa395
unii
413KH5ZJ73