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bosutinib

CHEBI:CHEBI_39112

Definition

An aminoquinoline that is 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline bearing additional cyano and methoxy substituents at positions 3 and 6 respectively.

Chemical Information

Molecular Formula
C26H29Cl2N5O3
Molecular Mass
530.44576
Charge
0
SMILES
COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl
InChI
InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
InChIKey
UBPYILGKFZZVDX-UHFFFAOYSA-N

Alternative Names

  • 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile
  • 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
  • Bosutinib
  • SKI 606
  • SKI-606

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:39112
DRON_00010000
1307619
oboInOwl#hasDbXref
Wikipedia:Bosutinib

Additional References

Wikipedia:Bosutinib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:39112
rxcui
2672328
active_ingredient_strength
1 kg/kg
package_marketing_start_date
20180221
pharm_class
Bcr-Abl Tyrosine Kinase Inhibitors [MoA]
manufacturer_name
U.S. Pharmaceuticals
active_ingredient_name
BOSUTINIB
package_description
30 TABLET, FILM COATED in 1 BOTTLE (0069-0193-01)
unii
844ZJE6I55
spl_set_id
d5929f91-6496-4c0e-97e8-0bd524e15763
upc
0300690135014
package_ndc
54893-0042-1
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
1307619
oboInOwl#hasDbXref
Wikipedia:Bosutinib
generic_name
Bosutinib
oboInOwl#id
CHEBI:39112
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
CAPSULE
marketing_start_date
20120904
labeler_name
U.S. Pharmaceuticals
brand_name
BOSULIF
brand_name_base
BOSULIF
product_ndc
0069-0193
application_number
NDA203341
spl_id
0cc44373-28e5-d2c2-e063-6394a90a0f2f
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38637
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_0081088
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23211
owl#annotatedSource
t211064
owl#someValuesFrom
t1126301