Discuss This Drug

darifenacin

CHEBI:CHEBI_391960

Definition

2-[(3S)-1-Ethylpyrrolidin-3-yl]-2,2-diphenylacetamide in which one of the hydrogens at the 2-position of the ethyl group is substituted by a 2,3-dihydro-1-benzofuran-5-yl group. It is a selective antagonist for the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions, and is used as the hydrobromide salt in the management of urinary incontinence.

Chemical Information

Molecular Formula
C28H30N2O2
Molecular Mass
426.55000
Charge
0
SMILES
[H][C@]1(CCN(CCc2ccc3OCCc3c2)C1)C(C(N)=O)(c1ccccc1)c1ccccc1
InChI
InChI=1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31)/t25-/m1/s1
InChIKey
HXGBXQDTNZMWGS-RUZDIDTESA-N

Alternative Names

  • (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide
  • 2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide
  • darifenacin
  • DARIFENACIN

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
136198
oboInOwl#hasDbXref
Wikipedia:Darifenacin
core#notation
CHEBI:391960

Additional References

Wikipedia:Darifenacin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

route
ORAL
package_marketing_start_date
15-APR-10
spl_id
32f7abd5-0ea6-450d-996e-31ba4ea7d699
package_ndc
65862-861-99
package_description
1000 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (65862-861-99)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
136198
oboInOwl#hasDbXref
Wikipedia:Darifenacin
oboInOwl#id
CHEBI:391960
generic_name
darifenacin hydrobromide
brand_name
Darifenacin 15 mg
brand_name_base
Darifenacin 15 mg
product_type
BULK INGREDIENT
listing_expiration_date
20241231
marketing_category
BULK INGREDIENT
dosage_form
TABLET, FILM COATED, EXTENDED RELEASE
marketing_start_date
20081117
labeler_name
POLYGEN PHARMACEUTICALS INC.
product_ndc
65862-861
application_number
ANDA206743
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_53784
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:391960
active_ingredient_name
DARIFENACIN HYDROBROMIDE
rxcui
485423
active_ingredient_strength
50 kg/50kg
pharm_class
Cholinergic Muscarinic Antagonists [MoA]
manufacturer_name
POLYGEN PHARMACEUTICALS INC.
unii
CR02EYQ8GV
spl_set_id
28ed5b58-46dd-4140-a877-4b422f780a94
upc
0365862862303
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_0080174
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_107777
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23232
owl#annotatedSource
t210634
owl#someValuesFrom
t1005970