Discuss This Drug

Timolol

CHEBI:CHEBI_39465

Definition

1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.

Chemical Information

Molecular Formula
C13H24N4O3S
Molecular Mass
316.42082
Charge
0
SMILES
CC(C)(C)NCC(O)COc1nsnc1N1CCOCC1
InChI
InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3
InChIKey
BLJRIMJGRPQVNF-UHFFFAOYSA-N

Alternative Names

  • 1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
10600
oboInOwl#hasDbXref
LINCS:LSM-4397
core#notation
CHEBI:39465

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
SOLUTION, GEL FORMING / DROPS
application_number
ANDA074261
product_ndc
51014-7520
marketing_start_date
19960115
labeler_name
BAUSCH & LOMB INCORPORATED
rxcui
1992305
active_ingredient_strength
5.12 mg/mL
nui
N0000000161
active_ingredient_name
TIMOLOL ANHYDROUS
unii
5JKY92S7BR
spl_set_id
036dc753-1698-4c69-9bcf-752c7061203c
upc
0372603540017
manufacturer_name
Apotex Corp
listing_expiration_date
20241231
route
OPHTHALMIC
spl_id
63a7516f-eb4b-42e3-b3ea-725c3a3098a4
package_ndc
82260-496-05
package_description
6 POUCH in 1 CARTON (82260-496-05) / 10 CONTAINER in 1 POUCH / .3 mL in 1 CONTAINER
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
10600
oboInOwl#hasDbXref
LINCS:LSM-4397
oboInOwl#hasAlternativeId
CHEBI:106362
oboInOwl#id
CHEBI:39465
generic_name
Timolol Maleate Ophthalmic Gel Forming Solution, 0.25%
brand_name
Timolol Maleate Ophthalmic Gel Forming Solution, 0.25%
brand_name_base
Timolol Maleate Ophthalmic Gel Forming Solution, 0.25%
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00020323
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_39469
package_marketing_start_date
02-AUG-07
core#notation
CHEBI:39465
pharm_class_moa
Adrenergic beta-Antagonists [MoA]
pharm_class
beta-Adrenergic Blocker [EPC]
pharm_class_epc
beta-Adrenergic Blocker [EPC]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_471
owl#annotatedSource
t213709
owl#someValuesFrom
t1049013