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carbidopa (anhydrous)

CHEBI:CHEBI_39585

Definition

3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.

Chemical Information

Molecular Formula
C10H14N2O4
Molecular Mass
226.22920
Charge
0
SMILES
C[C@@](Cc1ccc(O)c(O)c1)(NN)C(O)=O
InChI
InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1
InChIKey
TZFNLOMSOLWIDK-JTQLQIEISA-N

Alternative Names

  • (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
  • (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
  • (alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid
  • (S)-(-)-carbidopa
  • (S)-carbidopa
  • carbidopum
  • L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
  • L-alpha-methyldopahydrazine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Carbidopa
core#notation
CHEBI:39585

Additional References

Wikipedia:Carbidopa

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Additional Attributes

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CHEBI:39585
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