sitagliptin
CHEBI:CHEBI_40237
Definition
A triazolopyrazine that exhibits hypoglycemic activity.
Chemical Information
- Molecular Formula
- C16H15F6N5O
- Molecular Mass
- 407.31382
- Charge
- 0
- SMILES
- N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F
- InChI
- InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1
- InChIKey
- MFFMDFFZMYYVKS-SECBINFHSA-N
Alternative Names
- (2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE
- (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
- MK-0431
- sitagliptin
- sitagliptina
- sitagliptine
- sitagliptinum
Treatment Applications
-
brachydactyly type A1CView Disease →
DOID:0110977
-
hypoglycemic comaView Disease →
DOID:1607
-
hyperglycemiaView Disease →
DOID:4195
Drug Classification
-
trifluorobenzeneView Class →
CHEBI:83576
-
triazolopyrazineView Class →
CHEBI:48277
-
t213157
-
t213180
-
t213906
-
t213924
-
t214155
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 593411
- oboInOwl#hasDbXref
- Wikipedia:Sitagliptin
- core#notation
- CHEBI:40237
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- listing_expiration_date
- 20241231
- marketing_start_date
- 20100510
- labeler_name
- Moehs BCN SL
- spl_id
- 287bb5ab-ac9d-3a2f-e063-6394a90abb71
- application_number
- NDA021995
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 593411
- oboInOwl#hasDbXref
- Wikipedia:Sitagliptin
- oboInOwl#id
- CHEBI:40237
- generic_name
- Sitagliptin Hydrochloride Monohydrate
- product_ndc
- 60312-0109
- brand_name
- ZITUVIO
- brand_name_base
- ZITUVIO
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_68612
- product_type
- BULK INGREDIENT
- marketing_category
- EXPORT ONLY
- dosage_form
- POULTICE
- package_description
- 1 BAG in 1 DRUM (60312-0109-0) / 288461 TABLET in 1 BAG
- package_ndc
- 70710-1987-8
- route
- ORAL
- rxcui
- 2670451
- package_marketing_start_date
- 30-MAY-20
- manufacturer_name
- Zydus Pharmaceuticals (USA) Inc.
- core#notation
- CHEBI:40237
- active_ingredient_strength
- 850 mg/1
- active_ingredient_name
- SITAGLIPTIN HYDROCHLORIDE
- unii
- QFP0P1DV7Z
- pharm_class
- Dipeptidyl Peptidase 4 Inhibitors [MoA]
- nui
- N0000175913
- pharm_class_epc
- Dipeptidyl Peptidase 4 Inhibitor [EPC]
- pharm_class_moa
- Dipeptidyl Peptidase 4 Inhibitors [MoA]
- brand_name_suffix
- XR
- spl_set_id
- eb81a45f-05b8-49de-99ce-5089bd360d9b
- upc
- 0300060277313
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109368
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect23435
- owl#annotatedSource
- t214536
- owl#someValuesFrom
- t3268093