Cyclophosphamide
CHEBI:CHEBI_4027
Definition
A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.
Chemical Information
- Molecular Formula
- C7H15Cl2N2O2P
- Molecular Mass
- 261.08544
- Charge
- 0
- SMILES
- ClCCN(CCCl)P1(=O)NCCCO1
- InChI
- InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)
- InChIKey
- CMSMOCZEIVJLDB-UHFFFAOYSA-N
Alternative Names
- (+-)-Cyclophosphamide
- (RS)-Cyclophosphamide
- 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
- Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
- Cyclophosphamide anhydrous
- N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
- N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
Drug Classification
-
organochlorine compoundView Class →
CHEBI:36683
-
nitrogen mustardView Class →
CHEBI:37598
-
phosphorodiamideView Class →
CHEBI:35467
-
t213317
-
t213325
-
t213559
-
t213832
-
t213972
-
t214250
-
t214384
-
t214457
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 3002
- oboInOwl#hasDbXref
- Wikipedia:Cyclophosphamide
- core#notation
- CHEBI:4027
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- package_description
- 1 VIAL, SINGLE-DOSE in 1 CARTON (10019-944-01) / 50 mL in 1 VIAL, SINGLE-DOSE (10019-944-50)
- package_ndc
- 39822-0250-1
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- INJECTION, POWDER, FOR SOLUTION
- labeler_name
- STI Pharma LLC
- application_number
- ANDA214529
- product_ndc
- 76339-191
- rxcui
- 2679073
- active_ingredient_strength
- 500 mg/2.5mL
- manufacturer_name
- STI Pharma LLC
- package_marketing_start_date
- 20200730
- active_ingredient_name
- CYCLOPHOSPHAMIDE ANHYDROUS
- unii
- 6UXW23996M
- spl_set_id
- 34dbffee-80e0-49c3-90e8-95713a0b7fbe
- listing_expiration_date
- 20241231
- route
- INTRAVENOUS
- marketing_start_date
- 20090312
- spl_id
- 34dbffee-80e0-49c3-90e8-95713a0b7fbe
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 3002
- oboInOwl#hasDbXref
- Wikipedia:Cyclophosphamide
- prefixIRI
- CHEBI:4027
- oboInOwl#id
- CHEBI:4027
- generic_name
- cyclophosphamide injection, solution
- brand_name
- CYCLOPHOSPHAMIDE
- brand_name_base
- CYCLOPHOSPHAMIDE
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_35703
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- BFO_0000053
- http://purl.obolibrary.org/obo/DRON_00723855
- core#notation
- CHEBI:4027
- upc
- 0368001564229
- pharm_class_moa
- Alkylating Activity [MoA]
- pharm_class
- Alkylating Drug [EPC]
- pharm_class_epc
- Alkylating Drug [EPC]
- nui
- N0000175558
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_11126
- RO_0001022
- http://purl.obolibrary.org/obo/DOID_0040027
- owl#annotatedSource
- t214308
- owl#someValuesFrom
- t3004867