Cyclophosphamide

CHEBI:CHEBI_4027

Definition

A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.

Chemical Information

Molecular Formula
C7H15Cl2N2O2P
Molecular Mass
261.08544
Charge
0
SMILES
ClCCN(CCCl)P1(=O)NCCCO1
InChI
InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)
InChIKey
CMSMOCZEIVJLDB-UHFFFAOYSA-N

Alternative Names

  • (+-)-Cyclophosphamide
  • (RS)-Cyclophosphamide
  • 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
  • Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
  • Cyclophosphamide anhydrous
  • N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
  • N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3002
oboInOwl#hasDbXref
Wikipedia:Cyclophosphamide
core#notation
CHEBI:4027

Additional References

Wikipedia:Cyclophosphamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
route
INTRAVENOUS
marketing_start_date
20090312
spl_id
34dbffee-80e0-49c3-90e8-95713a0b7fbe
package_ndc
10019-944-01
labeler_name
Eugia US LLC
package_description
1 VIAL, SINGLE-DOSE in 1 CARTON (10019-944-01) / 50 mL in 1 VIAL, SINGLE-DOSE (10019-944-50)
rxcui
2679073
active_ingredient_strength
500 mg/2.5mL
manufacturer_name
STI Pharma LLC
package_marketing_start_date
20200730
active_ingredient_name
CYCLOPHOSPHAMIDE ANHYDROUS
unii
6UXW23996M
spl_set_id
34dbffee-80e0-49c3-90e8-95713a0b7fbe
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
INJECTION, POWDER, FOR SOLUTION
application_number
ANDA214529
product_ndc
76339-191
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3002
oboInOwl#hasDbXref
Wikipedia:Cyclophosphamide
prefixIRI
CHEBI:4027
oboInOwl#id
CHEBI:4027
generic_name
cyclophosphamide injection, solution
brand_name
CYCLOPHOSPHAMIDE
brand_name_base
CYCLOPHOSPHAMIDE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35703
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723855
core#notation
CHEBI:4027
upc
0368001564229
pharm_class_moa
Alkylating Activity [MoA]
pharm_class
Alkylating Drug [EPC]
pharm_class_epc
Alkylating Drug [EPC]
nui
N0000175558
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
RO_0001022
http://purl.obolibrary.org/obo/DOID_0040027
has_treatment
http://purl.obolibrary.org/obo/DOID_0081403
owl#annotatedSource
t214308
owl#someValuesFrom
t3004867