Discuss This Drug

Cyproheptadine

CHEBI:CHEBI_4046

Definition

The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Chemical Information

Molecular Formula
C21H21N
Molecular Mass
287.39810
Charge
0
SMILES
CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
InChI
InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
InChIKey
JJCFRYNCJDLXIK-UHFFFAOYSA-N

Alternative Names

  • 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
  • 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
  • 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
  • 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
  • 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
  • 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
  • 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine
  • 5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
  • ciproheptadina
  • cyproheptadine
  • cyproheptadine
  • Cyproheptadine
  • CYPROHEPTADINE
  • cyproheptadinum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:4046
DRON_00010000
3013
oboInOwl#hasDbXref
Wikipedia:Cyproheptadine

Additional References

Wikipedia:Cyproheptadine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

listing_expiration_date
20241231
labeler_name
QUAGEN PHARMACEUTICALS LLC
marketing_start_date
19830526
spl_id
c105fa1c-b613-4102-a556-1da23aad2b1c
application_number
ANDA206553
core#notation
CHEBI:4046
active_ingredient_name
CYPROHEPTADINE HYDROCHLORIDE
rxcui
866144
active_ingredient_strength
1 kg/kg
unii
2YHB6175DO
spl_set_id
1bfb14ad-b522-4ad6-8c9f-2d99dd0dce64
manufacturer_name
Westminster Pharmaceuticals, LLC
upc
0371205989309
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
route
ORAL
package_ndc
72162-2066-9
package_description
90 TABLET in 1 BOTTLE (72162-2066-9)
package_marketing_start_date
01-DEC-11
has_treatment
http://purl.obolibrary.org/obo/DOID_2493
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23497
owl#annotatedSource
t214505
owl#someValuesFrom
t3512358
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3013
oboInOwl#hasDbXref
Wikipedia:Cyproheptadine
oboInOwl#hasAlternativeId
CHEBI:605605
oboInOwl#id
CHEBI:4046
brand_name
cyproheptadine hydrochloride solution
brand_name_base
cyproheptadine hydrochloride solution
product_type
BULK INGREDIENT
dosage_form
SYRUP
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
generic_name
Cyproheptadine hydrochloride
product_ndc
72162-2066
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR