Discuss This Drug

ertapenem

CHEBI:CHEBI_404903

Definition

Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract.

Chemical Information

Molecular Formula
C22H25N3O7S
Molecular Mass
475.51500
Charge
0
SMILES
[H][C@]1(CN[C@@]([H])(C1)C(=O)Nc1cccc(c1)C(O)=O)SC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])[C@H]1C)C(O)=O
InChI
InChI=1S/C22H25N3O7S/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32)/t9-,10-,13+,14+,15-,16-/m1/s1
InChIKey
JUZNIMUFDBIJCM-ANEDZVCMSA-N

Alternative Names

  • (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid
  • (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (4R,5S,6S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • ertapenem
  • ERTAPENEM

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:404903
DRON_00010000
325642
oboInOwl#hasDbXref
Wikipedia:Ertapenem

Additional References

Wikipedia:Ertapenem

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:404903
pharm_class
Penem Antibacterial [EPC]
upc
0344567820016
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
325642
oboInOwl#hasDbXref
Wikipedia:Ertapenem
oboInOwl#id
CHEBI:404903
oboInOwl#hasAlternativeId
CHEBI:471574
generic_name
Ertapenem
brand_name
Ertapenem
brand_name_base
Ertapenem
product_type
BULK INGREDIENT
marketing_category
EXPORT ONLY
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
labeler_name
Savior Lifetec Corporation
marketing_start_date
20190829
product_ndc
59651-190
application_number
ANDA207647
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36047
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_60071
rxcui
1734686
listing_expiration_date
20241231
route
INTRAVENOUS
manufacturer_name
Savior Lifetec Corporation
package_marketing_start_date
21-NOV-01
active_ingredient_strength
50 kg/50kg
spl_id
31e5d8d4-d592-45a6-bedb-5bff8e3f362a
active_ingredient_name
ERTAPENEM SODIUM
package_ndc
59651-190-37
package_description
50 kg in 1 DRUM (59651-190-37)
unii
2T90KE67L0
spl_set_id
666c9f33-ea9e-4667-b8bd-f8b1b6b6be51
has_treatment
http://purl.obolibrary.org/obo/DOID_8337
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113904
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23517
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_60071
owl#annotatedSource
t214327
owl#someValuesFrom
t3005546