arformoterol

CHEBI:CHEBI_408174

Definition

An N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide in which both of the stereocentres have R configuration. The active enantiomer of formoterol, it is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema).

Chemical Information

Molecular Formula
C19H24N2O4
Molecular Mass
344.40490
Charge
0
SMILES
[H]C(=O)Nc1cc(ccc1O)[C@@H](O)CN[C@H](C)Cc1ccc(OC)cc1
InChI
InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1
InChIKey
BPZSYCZIITTYBL-YJYMSZOUSA-N

Alternative Names

  • (-)-formoterol
  • (R,R)-formoterol
  • arformoterol
  • N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:408174
DRON_00010000
304962
oboInOwl#hasDbXref
PMID:20406080

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:408174
rxcui
695935
pharm_class
beta2-Adrenergic Agonist [EPC]
package_marketing_start_date
02-JUL-12
manufacturer_name
Lifestar Pharma LLC
active_ingredient_strength
15 ug/2mL
active_ingredient_name
ARFORMOTEROL TARTRATE
unii
5P8VJ2I235
spl_set_id
6a498c49-042f-481f-bc5c-a2fc00dc5668
upc
0370748175019
package_description
30 POUCH in 1 CARTON (27437-055-30) / 1 VIAL, SINGLE-DOSE in 1 POUCH (27437-055-01) / 2 mL in 1 VIAL, SINGLE-DOSE
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
RESPIRATORY (INHALATION)
marketing_start_date
20220528
spl_id
8f4d31ae-a0b8-426a-92c8-7583ee585abd
package_ndc
72603-208-60
labeler_name
Inke SA
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_5147
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23598
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_63081
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_63107
owl#annotatedSource
t214483
owl#someValuesFrom
t3363383
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
304962
oboInOwl#hasDbXref
PMID:20406080
oboInOwl#id
CHEBI:408174
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
SOLUTION
generic_name
Arformoterol Tartrate Inhalation
brand_name
Arformoterol Tartrate Inhalation
brand_name_base
Arformoterol Tartrate Inhalation
product_ndc
72603-208
application_number
ANDA213762
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_35522
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_63107