Discuss This Drug

celecoxib

CHEBI:CHEBI_41423

Definition

A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 5 by 4-sulfamoylphenyl, trifluoromethyl and p-tolyl groups, respectively. A cyclooxygenase-2 inhibitor, it is used in the treatment of arthritis.

Chemical Information

Molecular Formula
C17H14F3N3O2S
Molecular Mass
381.370
Charge
0
SMILES
CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
InChI
InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)
InChIKey
RZEKVGVHFLEQIL-UHFFFAOYSA-N

Alternative Names

  • 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
  • Celebrex
  • celecoxib
  • Celecoxib
  • celecoxibum
  • p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Celecoxib
DRON_00010000
140587
core#notation
CHEBI:41423

Additional References

Wikipedia:Celecoxib

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
0591-3983
dosage_form
LIQUID
package_ndc
71335-2456-5
route
ORAL
spl_id
6447f5ba-6cf4-4b02-8f13-8a1d579bf90c
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
Jiangxi Synergy Pharmaceutical, Co., Ltd.
application_number
ANDA078857
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Celecoxib
DRON_00010000
140587
generic_name
celecoxib and tramadol hydrochloride
brand_name
Celecoxib 200 mg
brand_name_base
Celecoxib 200 mg
oboInOwl#hasAlternativeId
CHEBI:41418
oboInOwl#id
CHEBI:41423
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50629
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723854
marketing_start_date
19981002
package_description
60 CAPSULE in 1 BOTTLE (46708-270-60)
package_marketing_start_date
20181201
listing_expiration_date
20241231
manufacturer_name
SCILEX PHARMACEUTICALS INC.
active_ingredient_strength
44 mg/1
active_ingredient_name
CELECOXIB
nui
N0000175722
upc
0371205664305
spl_set_id
af9d962a-5469-2039-e053-2a95a90ad59f
core#notation
CHEBI:41423
pharm_class
Non-Steroidal [CS]
dea_schedule
CIV
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
pharm_class_epc
Nonsteroidal Anti-inflammatory Drug [EPC]
pharm_class_moa
Cyclooxygenase Inhibitors [MoA]
has_treatment
http://purl.obolibrary.org/obo/DOID_208
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23685
owl#annotatedSource
t214468
owl#someValuesFrom
t3847934
rxcui
2588484
unii
JCX84Q7J1L