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Eflornithine

CHEBI:CHEBI_41948

Definition

A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.

Chemical Information

Molecular Formula
C6H12F2N2O2
Molecular Mass
182.16850
Charge
0
SMILES
NCCCC(N)(C(F)F)C(O)=O
InChI
InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)
InChIKey
VLCYCQAOQCDTCN-UHFFFAOYSA-N

Alternative Names

  • 2-(difluoromethyl)ornithine
  • 2,5-diamino-2-(difluoromethyl)pentanoic acid
  • alpha-(Difluoromethyl)-DL-ornithine
  • alpha-difluoromethylornithine
  • ALPHA-DIFLUOROMETHYLORNITHINE
  • DFMO
  • DL-Ornithine, 2-(difluoromethyl)-
  • Eflornithine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:41948
DRON_00010000
569
oboInOwl#hasDbXref
Wikipedia:Eflornithine

Additional References

Wikipedia:Eflornithine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_18257
core#notation
CHEBI:41948
active_ingredient_strength
4170 mg/30g
package_marketing_start_date
31-MAR-05
pharm_class
Decarboxylase Inhibitors [MoA]
manufacturer_name
USWM, LLC
active_ingredient_name
EFLORNITHINE HYDROCHLORIDE
package_description
500 g in 1 CONTAINER (71052-825-50)
rxcui
2673205
unii
4NH22NDW9H
spl_set_id
d0842c09-4f4f-5209-e053-2a95a90a54d6
package_ndc
71052-825-25
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
569
oboInOwl#hasDbXref
Wikipedia:Eflornithine
oboInOwl#hasAlternativeId
CHEBI:4761
oboInOwl#id
CHEBI:41948
generic_name
Eflornithine HCl Monohydrate
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
route
TOPICAL
dosage_form
CREAM
marketing_start_date
20120209
labeler_name
USWM, LLC
brand_name
Florexa
brand_name_base
Florexa
product_ndc
71052-825
application_number
NDA215500
spl_id
16755d00-6be2-0a66-e063-6394a90a2030
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36335
has_treatment
http://purl.obolibrary.org/obo/DOID_12054
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23779
owl#annotatedSource
t217960
owl#someValuesFrom
t551015