abacavir
CHEBI:CHEBI_421707
Definition
A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection.
Chemical Information
- Molecular Formula
- C14H18N6O
- Molecular Mass
- 286.339
- Charge
- 0
- SMILES
- C=12N(C=NC1C(NC3CC3)=NC(=N2)N)[C@H]4C=C[C@H](C4)CO
- InChI
- InChI=1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1
- InChIKey
- MCGSCOLBFJQGHM-SCZZXKLOSA-N
Alternative Names
- {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
- {(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
- abacavir
- Abacavir
- ABC
Drug Classification
-
2,6-diaminopurinesView Class →
CHEBI:38001
-
t216891
-
t217467
-
t217576
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:421707
- oboInOwl#hasDbXref
- Wikipedia:Abacavir
- DRON_00010000
- 190521
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- dosage_form
- SOLUTION
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- marketing_start_date
- 19981217
- labeler_name
- REMEDYREPACK INC.
- application_number
- ANDA091144
- product_ndc
- 70710-1049
- core#notation
- CHEBI:421707
- rxcui
- 2598352
- active_ingredient_strength
- 50 kg/50kg
- pharm_class
- Cytochrome P450 1A1 Inhibitors [MoA]
- nui
- N0000175656
- pharm_class_epc
- Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]
- pharm_class_moa
- Nucleoside Reverse Transcriptase Inhibitors [MoA]
- active_ingredient_name
- ABACAVIR
- unii
- 1Q1V9V5WYQ
- spl_set_id
- 4dd14728-02b4-4e75-b9c6-227be7816d5b
- manufacturer_name
- Mylan Pharmaceuticals Inc.
- upc
- 0331722557603
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- package_marketing_start_date
- 17-DEC-98
- package_description
- 20 kg in 1 DRUM (63379-049-00)
- package_ndc
- 69097-362-02
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Abacavir
- DRON_00010000
- 190521
- generic_name
- abacavir sulfate and lamivudine
- brand_name
- EPZICOM
- brand_name_base
- EPZICOM
- oboInOwl#hasAlternativeId
- CHEBI:525912
- prefixIRI
- CHEBI:421707
- oboInOwl#id
- CHEBI:421707
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_53756
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- listing_expiration_date
- 20241231
- route
- ORAL
- spl_id
- 2f5e97a9-9131-4bad-970e-88081d2ccafc
- RO_0001022
- http://purl.obolibrary.org/obo/DOID_0040007
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0040007
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect48
- owl#annotatedSource
- t218025
- owl#someValuesFrom
- t3866939