erythromycin A
CHEBI:CHEBI_42355
Definition
An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively.
Chemical Information
- Molecular Formula
- C37H67NO13
- Molecular Mass
- 733.92680
- Charge
- 0
- SMILES
- CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
- InChI
- InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
- InChIKey
- ULGZDMOVFRHVEP-RWJQBGPGSA-N
Alternative Names
- 3''-O-demethylerythromycin
- Abomacetin
- eritromicina
- erthromycin
- erythromycin
- erythromycin
- Erythromycin
- ERYTHROMYCIN
- Erythromycin A
- ERYTHROMYCIN A
- Erythromycin C
- erythromycine
- erythromycinum
- (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyloxy)-14-ethyl-7,12,13-trihydroxy-6-[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyloxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
- (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
Drug Classification
-
cyclic ketoneView Class →
CHEBI:3992
-
erythromycinView Class →
CHEBI:48923
-
ErythromycinView Class →
CHEBI:48923
-
t217384
-
t217584
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Reaxys:75279
- core#notation
- CHEBI:42355
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- dosage_form
- GRANULE, FOR SUSPENSION
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- labeler_name
- SM BIOMED SDN.BHD.
- application_number
- NDA050617
- product_ndc
- 52536-105
- brand_name_base
- Erythromycin ethylsuccinate
- route
- OPHTHALMIC
- package_ndc
- 52334-001-01
- spl_id
- 0d6bef61-c1ba-1b9c-e063-6294a90a8bda
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Reaxys:75279
- oboInOwl#hasAlternativeId
- CHEBI:4843
- oboInOwl#id
- CHEBI:42355
- generic_name
- Erythromycin Estolate
- brand_name
- Ery
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_48844
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_64268
- package_description
- 25 kg in 1 CARTON (52334-001-01)
- listing_expiration_date
- 20241231
- marketing_start_date
- 20130910
- rxcui
- 1668264
- unii
- 33H58I7GLQ
- spl_set_id
- bccdb8f3-b5f5-4f07-8ddb-8811d5c1b73c
- manufacturer_name
- ARMAS PHARMACEUTICALS INC.
- package_marketing_start_date
- 20200707
- active_ingredient_name
- ERYTHROMYCIN ESTOLATE
- active_ingredient_strength
- 1200 mg/30g
- nui
- N0000175877
- upc
- 0375834294018
- core#notation
- CHEBI:42355
- pharm_class_epc
- Macrolide [EPC]
- pharm_class
- Macrolide [EPC]
- pharm_class_cs
- Macrolides [CS]
- pharm_class_pe
- Decreased Sebaceous Gland Activity [PE]
- brand_name_suffix
- 400
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect23858
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_64268
- owl#annotatedSource
- t218036
- owl#someValuesFrom
- t265103