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Dapsone

CHEBI:CHEBI_4325

Definition

A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy.

Chemical Information

Molecular Formula
C12H12N2O2S
Molecular Mass
248.30100
Charge
0
SMILES
Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
InChI
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChIKey
MQJKPEGWNLWLTK-UHFFFAOYSA-N

Alternative Names

  • 1,1'-sulfonylbis(4-aminobenzene)
  • 4-(4-amino-benzenesulfonyl)-phenylamine
  • 4-(4-aminophenylsulfonyl)aniline
  • 4-(4-aminophenylsulfonyl)benzenamine
  • 4-aminophenyl sulfone
  • 4,4'-dapsone
  • 4,4'-diaminodiphenyl sulfone
  • 4,4'-sulfonylbisaniline
  • 4,4'-Sulfonylbisbenzenamine
  • 4,4'-sulfonyldianiline
  • bis(4-aminophenyl)sulfone
  • Bis(p-aminophenyl) sulfone
  • DADPS
  • dapsona
  • dapsone
  • Dapsone
  • DAPSONE
  • dapsonum
  • DDS
  • Diaphenylsulfone
  • DIAPHENYLSULFONE
  • p-aminophenyl sulfone
  • p,p-sulphonylbisbenzamine
  • p,p-sulphonylbisbenzenamine
  • p,p'-diaminodiphenyl sulfone

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3108
oboInOwl#hasDbXref
Wikipedia:Dapsone
core#notation
CHEBI:4325

Additional References

Wikipedia:Dapsone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

package_description
20 kg in 1 DRUM (46438-0645-1)
package_ndc
50218-008-10
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
GEL
labeler_name
Almirall, LLC
marketing_start_date
20010309
application_number
ANDA213847
product_ndc
14474-026
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3108
oboInOwl#hasDbXref
Wikipedia:Dapsone
oboInOwl#hasAlternativeId
CHEBI:226356
oboInOwl#id
CHEBI:4325
generic_name
Dapsone Micronized
brand_name
ACZONE
brand_name_base
ACZONE
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38068
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_78360
has_treatment
http://purl.obolibrary.org/obo/DOID_0070136
active_ingredient_name
DAPSONE
rxcui
1741907
manufacturer_name
Almirall, LLC
active_ingredient_strength
35 kg/35kg
unii
8W5C518302
spl_set_id
e04da0a1-d02a-487d-a931-a31034738fdd
nui
M0020791
package_marketing_start_date
01-JUL-19
upc
0307130886604
core#notation
CHEBI:4325
pharm_class_epc
Sulfone [EPC]
pharm_class
Sulfones [CS]
pharm_class_cs
Sulfones [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
listing_expiration_date
20241231
route
TOPICAL
spl_id
d309420e-771a-2603-e053-2995a90aaf75
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect23980
owl#annotatedSource
t218044
owl#someValuesFrom
t931781