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Dexfenfluramine

CHEBI:CHEBI_439329

Definition

The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.

Chemical Information

Molecular Formula
C12H16F3N
Molecular Mass
231.25730
Charge
0
SMILES
CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F
InChI
InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
InChIKey
DBGIVFWFUFKIQN-VIFPVBQESA-N

Alternative Names

  • (+)-fenfluramine
  • (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
  • (S)-fenfluramine
  • (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
  • d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine
  • dexfenfluramina
  • dexfenfluramine
  • dexfenfluraminum
  • dextrofenfluramine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3268
oboInOwl#hasDbXref
PMID:16257207
core#notation
CHEBI:439329

Additional References

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Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3268
oboInOwl#hasDbXref
PMID:16257207
oboInOwl#id
CHEBI:439329
core#notation
CHEBI:439329
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723856
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_521051
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#annotatedSource
t218059
owl#someValuesFrom
t712030