Discuss This Drug

Metyrapone

CHEBI:CHEBI_44241

Definition

An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Chemical Information

Molecular Formula
C14H14N2O
Molecular Mass
226.27380
Charge
0
SMILES
CC(C)(C(=O)c1cccnc1)c1cccnc1
InChI
InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
InChIKey
FJLBFSROUSIWMA-UHFFFAOYSA-N

Alternative Names

  • 2-methyl-1,2-dipyridin-3-ylpropan-1-one
  • metirapona
  • Metopiron
  • Metopirone
  • metyrapone
  • Metyrapone
  • METYRAPONE
  • metyraponum

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
6923
oboInOwl#hasDbXref
Wikipedia:Metyrapone
core#notation
CHEBI:44241

Additional References

Wikipedia:Metyrapone

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

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chebi_ontology
DRON_00010000
6923
oboInOwl#hasDbXref
Wikipedia:Metyrapone
oboInOwl#hasAlternativeId
CHEBI:6911
oboInOwl#id
CHEBI:44241
core#notation
CHEBI:44241
brand_name
Metopirone
brand_name_base
Metopirone
generic_name
METYRAPONE
active_ingredient_name
METYRAPONE
rxcui
105450
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
CAPSULE, GELATIN COATED
active_ingredient_strength
1 kg/kg
product_ndc
55361-0011
labeler_name
Catalent Germany Eberbach GmbH
marketing_start_date
19620125
spl_id
191ce2e2-96f4-7f11-e063-6294a90a17b7
package_ndc
55361-0011-2
package_description
1 BAG in 1 CARTON (55361-0011-2) / 12000 CAPSULE in 1 BAG
package_marketing_start_date
14-AUG-14
manufacturer_name
HRA Pharma Rare Diseases
application_number
NDA012911
unii
ZS9KD92H6V
spl_set_id
3a27d0ef-83a7-4e1c-9430-46a3326ee8d8
nui
N0000175921
pharm_class_epc
Adrenal Steroid Synthesis Inhibitor [EPC]
pharm_class
Adrenal Steroid Synthesis Inhibitors [MoA]
pharm_class_moa
Adrenal Steroid Synthesis Inhibitors [MoA]
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_76798
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http://www.w3.org/2002/07/owl#Class
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http://purl.obolibrary.org/obo/DOID_0070547
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https://w3id.org/def/predibionto#has_side_effect24126
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t217991
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t830647