Discuss This Drug

hydroxyurea

CHEBI:CHEBI_44423

Definition

A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease.

Chemical Information

Molecular Formula
CH4N2O2
Molecular Mass
76.05474
Charge
0
SMILES
NC(=O)NO
InChI
InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChIKey
VSNHCAURESNICA-UHFFFAOYSA-N

Alternative Names

  • carbamohydroxamic acid
  • carbamohydroximic acid
  • carbamoyl oxime
  • carbamyl hydroxamate
  • hidroxicarbamida
  • hydrea
  • Hydroxycarbamid
  • hydroxycarbamide
  • Hydroxycarbamide
  • hydroxycarbamidum
  • Hydroxyharnstoff
  • hydroxyurea
  • Hydroxyurea
  • N-carbamoylhydroxylamine
  • N-hydroxyurea
  • N-HYDROXYUREA
  • oxyurea

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
5552
oboInOwl#hasDbXref
Wikipedia:Hydroxyurea
core#notation
CHEBI:44423

Additional References

Wikipedia:Hydroxyurea

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
listing_expiration_date
20241231
route
ORAL
dosage_form
SOLUTION
marketing_start_date
19981019
application_number
ANDA075143
labeler_name
Nova Laboratories, Ltd.
spl_id
0f248c9e-a690-1bc3-e063-6394a90a274d
product_ndc
49452-3650
package_marketing_start_date
19981019
package_ndc
17337-0022-2
package_description
25 kg in 1 DRUM (17337-0022-2)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
5552
oboInOwl#hasDbXref
Wikipedia:Hydroxyurea
oboInOwl#hasAlternativeId
CHEBI:5816
oboInOwl#id
CHEBI:44423
generic_name
HYDROXYUREA
brand_name
XROMI
brand_name_base
XROMI
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_74213
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
core#notation
CHEBI:44423
rxcui
2696079
active_ingredient_strength
500 g/500g
manufacturer_name
Nova Laboratories, Ltd.
active_ingredient_name
HYDROXYUREA
unii
X6Q56QN5QC
spl_set_id
862583ff-6d5c-3f7d-e3bd-352fb0400928
nui
M0022315
pharm_class_epc
Antimetabolite [EPC]
pharm_class
Urea [CS]
pharm_class_cs
Urea [CS]
upc
0305550882022
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_3680
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24150
owl#annotatedSource
t218057
owl#someValuesFrom
t807155