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Dextromethorphan

CHEBI:CHEBI_4470

Definition

A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.

Chemical Information

Molecular Formula
C18H25NO
Molecular Mass
271.404
Charge
0
SMILES
C=1C=2C[C@H]3[C@@]4([C@](C2C=C(C1)OC)(CCCC4)CCN3C)[H]
InChI
InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
InChIKey
MKXZASYAUGDDCJ-NJAFHUGGSA-N

Alternative Names

  • (+)-3-methoxy-N-methylmorphinan
  • (+)-dextromethorphan
  • (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
  • (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan
  • 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
  • 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
  • Albutussin
  • Antussan
  • BA 2666
  • BA-2666
  • Balminil DM
  • Benylin DM
  • Calmylin
  • d-Methorphan
  • D-methorphan
  • Delsym
  • destrometerfano
  • dextromethorfan
  • dextromethorphan
  • dextromethorphane
  • dextromethorphanum
  • dextrometorfano
  • Dextromorphan
  • DXM
  • Medicon
  • Romilar
  • Tusilan

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3289
oboInOwl#hasDbXref
Wikipedia:Dextromethorphan
core#notation
CHEBI:4470

Additional References

Wikipedia:Dextromethorphan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3289
oboInOwl#hasDbXref
Wikipedia:Dextromethorphan
oboInOwl#id
CHEBI:4470
core#notation
CHEBI:4470
oboInOwl#hasAlternativeId
CHEBI:92579
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_29133
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_146176
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723856
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
owl#someValuesFrom
t1109669
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6612
owl#annotatedSource
t221439