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Dextromethorphan

CHEBI:CHEBI_4470

Definition

A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.

Chemical Information

Molecular Formula
C18H25NO
Molecular Mass
271.404
Charge
0
SMILES
C=1C=2C[C@H]3[C@@]4([C@](C2C=C(C1)OC)(CCCC4)CCN3C)[H]
InChI
InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
InChIKey
MKXZASYAUGDDCJ-NJAFHUGGSA-N

Alternative Names

  • (+)-3-methoxy-N-methylmorphinan
  • (+)-dextromethorphan
  • (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
  • (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan
  • 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
  • 3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
  • Albutussin
  • Antussan
  • BA 2666
  • BA-2666
  • Balminil DM
  • Benylin DM
  • Calmylin
  • d-Methorphan
  • D-methorphan
  • Delsym
  • destrometerfano
  • dextromethorfan
  • dextromethorphan
  • dextromethorphane
  • dextromethorphanum
  • dextrometorfano
  • Dextromorphan
  • DXM
  • Medicon
  • Romilar
  • Tusilan

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3289
oboInOwl#hasDbXref
Wikipedia:Dextromethorphan
core#notation
CHEBI:4470

Additional References

Wikipedia:Dextromethorphan

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

brand_name
Tusnel SF
product_ndc
62331-004
brand_name_base
BupropiDex
generic_name
Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl
marketing_start_date
20181109
labeler_name
Walgreen Company
dosage_form
CRYSTAL
product_type
BULK INGREDIENT
marketing_category
EXPORT ONLY
application_number
ANDA088864
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3289
oboInOwl#hasDbXref
Wikipedia:Dextromethorphan
oboInOwl#id
CHEBI:4470
oboInOwl#hasAlternativeId
CHEBI:92579
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_29133
chebi#is_enantiomer_of
http://purl.obolibrary.org/obo/CHEBI_146176
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723856
listing_expiration_date
20241231
spl_id
b085b437-2ed4-4a8e-bca7-9cd1a4df310e
package_ndc
62331-004-31
route
ORAL
package_description
1 BOTTLE, PLASTIC in 1 BOX (55301-382-08) / 237 mL in 1 BOTTLE, PLASTIC
package_marketing_start_date
13-FEB-02
active_ingredient_strength
396 mg/15mL
active_ingredient_name
HEXYLRESORCINOL
owl#someValuesFrom
t4001012
pharm_class
Uncompetitive NMDA Receptor Antagonists [MoA]
pharm_class_epc
Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC]
pharm_class_pe
Increased Respiratory Secretions [PE]
pharm_class_moa
Uncompetitive NMDA Receptor Antagonists [MoA]
upc
0859156006226
manufacturer_name
Amerisource Bergen
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect6612
owl#annotatedSource
t221439
nui
N0000182147
spl_set_id
da1f1ef9-a974-4998-8e1d-c1d999596943
rxcui
2362250
unii
6K9YKD48Y4
core#notation
CHEBI:4470
brand_name_suffix
COUGH
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class