Isoproterenol
CHEBI:CHEBI_4495
Definition
A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Chemical Information
- Molecular Formula
- C8H7ClN2O2S
- Molecular Mass
- 230.67100
- Charge
- 0
- SMILES
- CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1
- InChI
- InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
- InChIKey
- GDLBFKVLRPITMI-UHFFFAOYSA-N
Alternative Names
- 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- Diazossido
- diazoxide
- Diazoxide
- diazoxido
- diazoxidum
- Eudemine
Treatment Applications
-
transient neonatal diabetes mellitusView Disease →
DOID:0060334
Drug Classification
-
sulfoneView Class →
CHEBI:35850
-
organochlorine compoundView Class →
CHEBI:36683
-
benzothiadiazineView Class →
CHEBI:50265
-
t220679
-
t220793
-
t220811
-
t220893
-
t221058
-
t221068
-
t221087
-
t221165
-
t221342
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- oboInOwl#hasDbXref
- Wikipedia:Diazoxide
- DRON_00010000
- 6054
- core#notation
- CHEBI:4495
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Diazoxide
- DRON_00010000
- 6054
- oboInOwl#id
- CHEBI:4495
- oboInOwl#hasAlternativeId
- CHEBI:6046
- generic_name
- DIAZOXIDE
- brand_name
- Proglycem
- brand_name_base
- Proglycem
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- SUSPENSION
- labeler_name
- Guangan Kingday Pharma & Chem Co., Ltd.
- product_ndc
- 58159-039
- application_number
- ANDA211050
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38633
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- core#notation
- CHEBI:4495
- rxcui
- 207634
- package_marketing_start_date
- 10-AUG-23
- active_ingredient_strength
- 35 kg/35kg
- manufacturer_name
- e5 Pharma, LLC
- active_ingredient_name
- DIAZOXIDE
- unii
- O5CB12L4FN
- spl_set_id
- c0237320-2d3f-4907-a4d3-08f138aa4ca8
- upc
- 0302541010198
- package_description
- 5 kg in 1 DRUM (58159-039-05)
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- listing_expiration_date
- 20241231
- route
- ORAL
- marketing_start_date
- 20140708
- spl_id
- 7fd3623f-6cf1-49ff-aa86-f2f941166ea3
- package_ndc
- 58159-039-07
- has_treatment
- http://purl.obolibrary.org/obo/DOID_5572
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_101360
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect24268
- owl#annotatedSource
- t221546
- owl#someValuesFrom
- t3363794