Discuss This Drug

Pentamidine

CHEBI:CHEBI_45081

Definition

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.

Chemical Information

Molecular Formula
C19H24N4O2
Molecular Mass
340.420
Charge
0
SMILES
C(CCCOC1=CC=C(C=C1)C(N)=N)COC2=CC=C(C=C2)C(N)=N
InChI
InChI=1S/C19H24N4O2/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23)
InChIKey
XDRYMKDFEDOLFX-UHFFFAOYSA-N

Alternative Names

  • 1,5-bis(4-amidinophenoxy)pentane
  • 4,4'-(1,5-pentanediylbis(oxy))bis-benzenecarboximidamide
  • 4,4'-(pentamethylenedioxy)dibenzamidine
  • 4,4'-[pentane-1,5-diylbis(oxy)]dibenzenecarboximidamide
  • 4,4'-Diamidinodiphenoxypentane
  • p,p'-(pentamethylenedioxy)dibenzamidine
  • pentamidin
  • pentamidine
  • Pentamidine

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:45081
DRON_00010000
7994
oboInOwl#hasDbXref
Wikipedia:Pentamidine

Additional References

Wikipedia:Pentamidine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:45081
rxcui
861604
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INHALANT
route
INTRAVENOUS
marketing_start_date
20010116
package_marketing_start_date
20010116
labeler_name
XGen Pharmaceuticals DJB, Inc.
manufacturer_name
XGen Pharmaceuticals DJB, Inc.
pharm_class
Antiprotozoal [EPC]
active_ingredient_strength
300 mg/6mL
active_ingredient_name
PENTAMIDINE ISETHIONATE
product_ndc
11712-788
spl_id
5bec551d-4299-06b7-e053-2a91aa0acb62
package_ndc
11712-788-01
package_description
25 kg in 1 DRUM (11712-788-01)
brand_name_base
Pentam 300
application_number
NDA019264
unii
V2P3K60DA2
spl_set_id
cc2b635e-4840-4dc3-a177-5484371680e8
upc
0363323113018
brand_name
Pentamidine Isethionate
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
7994
oboInOwl#hasDbXref
Wikipedia:Pentamidine
oboInOwl#hasAlternativeId
CHEBI:7976
oboInOwl#id
CHEBI:45081
generic_name
pentamidine isethionate
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_67079
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#is_conjugate_base_of
http://purl.obolibrary.org/obo/CHEBI_64383
has_treatment
http://purl.obolibrary.org/obo/DOID_9065
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24287
chebi#is_conjugate_acid_of
http://purl.obolibrary.org/obo/CHEBI_64383
owl#annotatedSource
t221548
owl#someValuesFrom
t3363292