Discuss This Drug

pyrazinecarboxamide

CHEBI:CHEBI_45285

Definition

A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.

Chemical Information

Molecular Formula
C5H5N3O
Molecular Mass
123.11282
Charge
0
SMILES
NC(=O)c1cnccn1
InChI
InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChIKey
IPEHBUMCGVEMRF-UHFFFAOYSA-N

Alternative Names

  • 2-carbamylpyrazine
  • 2-pyrazinecarboxamide
  • pyrazinamida
  • pyrazinamide
  • Pyrazinamide
  • pyrazinamidum
  • pyrazine carboxamide
  • pyrazine-2-carboxamide
  • PYRAZINE-2-CARBOXAMIDE
  • pyrazineamide
  • Pyrazinoic acid amide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:45285
DRON_00010000
8987
oboInOwl#hasDbXref
Wikipedia:Pyrazinamide

Additional References

Wikipedia:Pyrazinamide

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:45285
pharm_class_epc
Antimycobacterial [EPC]
pharm_class
Antimycobacterial [EPC]
upc
0333342447111
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
8987
oboInOwl#hasDbXref
Wikipedia:Pyrazinamide
oboInOwl#hasAlternativeId
CHEBI:8656
oboInOwl#id
CHEBI:45285
generic_name
pyrazinamide tablet
brand_name
PYRAZINAMIDE
brand_name_base
PYRAZINAMIDE
product_type
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
POWDER
marketing_category
BULK INGREDIENT
marketing_start_date
19990511
labeler_name
MARLEX PHARMACEUTICALS, INC
product_ndc
11712-815
application_number
ANDA212541
spl_id
5bec551d-42a9-06b7-e053-2a91aa0acb62
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50266
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
rxcui
198181
route
ORAL
active_ingredient_strength
1 kg/kg
package_marketing_start_date
11-MAY-99
nui
N0000175483
manufacturer_name
MARLEX PHARMACEUTICALS, INC
active_ingredient_name
PYRAZINAMIDE
package_ndc
11712-815-01
package_description
25 kg in 1 DRUM (11712-815-01)
unii
2KNI5N06TI
spl_set_id
ab904db1-1fbc-40a3-ad92-ece998dc49e2
has_treatment
http://purl.obolibrary.org/obo/DOID_587
owl#annotatedSource
t221549
owl#someValuesFrom
t936387