ciclopirox
CHEBI:CHEBI_453011
Definition
A cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, respectively. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections.
Chemical Information
- Molecular Formula
- C12H17NO2
- Molecular Mass
- 207.26890
- Charge
- 0
- SMILES
- Cc1cc(C2CCCCC2)n(O)c(=O)c1
- InChI
- InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
- InChIKey
- SCKYRAXSEDYPSA-UHFFFAOYSA-N
Alternative Names
- 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone
- 6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
- ciclopirox
- ciclopiroxum
Drug Classification
-
hydroxypyridone antifungal drugView Class →
CHEBI:87130
-
t220345
-
t220683
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:453011
- DRON_00010000
- 21090
- oboInOwl#hasDbXref
- Wikipedia:Ciclopirox
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- listing_expiration_date
- 20241231
- labeler_name
- Shanghai Pharma Group Changzhou Kony Pharmaceutical Co., Ltd.
- marketing_start_date
- 20050412
- spl_id
- 91785959-a455-4ecf-8b03-5b3f114bd7bb
- application_number
- ANDA077364
- rxcui
- 544743
- manufacturer_name
- Preferred Pharmaceuticals Inc.
- package_marketing_start_date
- 20061214
- unii
- 19W019ZDRJ
- package_description
- 1 TUBE in 1 CARTON (0574-2061-01) / 100 g in 1 TUBE
- core#notation
- CHEBI:453011
- active_ingredient_strength
- 7.7 mg/mL
- active_ingredient_name
- CICLOPIROX
- spl_set_id
- aaa27021-68a6-486c-9095-56de1140ca2d
- pharm_class_pe
- Decreased RNA Replication [PE]
- pharm_class
- Protein Synthesis Inhibitors [MoA]
- pharm_class_moa
- Protein Synthesis Inhibitors [MoA]
- nui
- N0000000150
- upc
- 0307130638159
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_8741
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect24506
- owl#annotatedSource
- t221372
- owl#someValuesFrom
- t580575
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 21090
- oboInOwl#hasDbXref
- Wikipedia:Ciclopirox
- oboInOwl#id
- CHEBI:453011
- generic_name
- Ciclopirox olamine
- brand_name
- Loprox
- brand_name_base
- Loprox
- dosage_form
- SHAMPOO
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- product_ndc
- 49706-1440
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_59010
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- route
- TOPICAL
- package_ndc
- 49706-1440-0