Discuss This Drug

rifabutin

CHEBI:CHEBI_45367

Chemical Information

Molecular Formula
C46H62N4O11
Molecular Mass
847.00484
Charge
0
SMILES
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4C(=O)C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)=C1NC5(CCN(CC5)CC(C)C)N=C1c4c3C2=O
InChI
InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1
InChIKey
ATEBXHFBFRCZMA-VXTBVIBXSA-N

Alternative Names

  • 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV
  • 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S
  • 4-N-isobutylspiropiperidylrifamycin S
  • Mycobutin (TN)
  • Rifabutin

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:45367
DRON_00010000
55672
oboInOwl#hasDbXref
Wikipedia:Rifabutin

Additional References

Wikipedia:Rifabutin

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:45367
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
55672
oboInOwl#hasDbXref
Wikipedia:Rifabutin
oboInOwl#hasAlternativeId
CHEBI:8857
oboInOwl#id
CHEBI:45367
generic_name
Rifabutin USP-EP
brand_name
Rifabutin
brand_name_base
Rifabutin
rxcui
198200
product_type
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE
active_ingredient_strength
1 kg/kg
marketing_start_date
20140326
package_marketing_start_date
20140407
labeler_name
Novitium Pharma LLC
manufacturer_name
Novitium Pharma LLC
nui
N0000175501
pharm_class
Rifamycin Antimycobacterial [EPC]
pharm_class_cs
Rifamycins [CS]
pharm_class_epc
Rifamycin Antimycobacterial [EPC]
product_ndc
17337-0059
application_number
ANDA090033
spl_id
79869230-395d-422a-e053-2991aa0a0106
spl_set_id
df7d4103-42e4-4e4f-e053-2a95a90a8ce8
active_ingredient_name
RIFABUTIN
package_ndc
17337-0059-1
package_description
1 BAG in 1 DRUM (17337-0059-1) / 1 BAG in 1 BAG / 25 kg in 1 BAG
unii
1W306TDA6S
upc
0370954041108
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_33231
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_2757
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24569
owl#annotatedSource
t221547
owl#someValuesFrom
t3463708