Discuss This Drug

Vorinostat

CHEBI:CHEBI_45716

Definition

A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Chemical Information

Molecular Formula
C14H20N2O3
Molecular Mass
264.32020
Charge
0
SMILES
ONC(=O)CCCCCCC(=O)Nc1ccccc1
InChI
InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
InChIKey
WAEXFXRVDQXREF-UHFFFAOYSA-N

Alternative Names

  • N-hydroxy-N'-phenyloctanediamide
  • octanedioic acid hydroxyamide phenylamide
  • SAHA
  • SHH
  • Suberanilohydroxamic acid
  • suberoylanilide hydroxamic acid
  • vorinostat
  • vorinostatum
  • Zolinza

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:45716
DRON_00010000
194337
oboInOwl#hasDbXref
Wikipedia:Vorinostat

Additional References

Wikipedia:Vorinostat

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:45716
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
194337
oboInOwl#hasDbXref
Wikipedia:Vorinostat
oboInOwl#id
CHEBI:45716
generic_name
Vorinostat Fine
listing_expiration_date
20241231
active_ingredient_strength
55 kg/55kg
dosage_form
CAPSULE
marketing_start_date
20061006
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
labeler_name
MAEDA INC
package_marketing_start_date
06-OCT-06
product_ndc
65392-3102
spl_id
d21ceb6d-2be7-f37b-e053-2995a90a5014
active_ingredient_name
VORINOSTAT
package_ndc
65392-3102-0
package_description
55 kg in 1 DRUM (65392-3102-0)
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_9300
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_61115
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_4788
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_111688
owl#annotatedSource
t221521
owl#someValuesFrom
t979151