Tacrine
CHEBI:CHEBI_45980
Definition
A member of the class of acridines that is 1,2,3,4-tetrahydroacridine substituted by an amino group at position 9. It is used in the treatment of Alzheimer's disease.
Chemical Information
- Molecular Formula
- C13H14N2
- Molecular Mass
- 198.26374
- Charge
- 0
- SMILES
- Nc1c2CCCCc2nc2ccccc12
- InChI
- InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)
- InChIKey
- YLJREFDVOIBQDA-UHFFFAOYSA-N
Alternative Names
- 1,2,3,4-tetrahydro-9-acridinamine
- 1,2,3,4-tetrahydro-9-aminoacridine
- 1,2,3,4-tetrahydroacridin-9-amine
- 5-amino-6,7,8,9-tetrahydroacridine
- 9-amino-1,2,3,4-tetrahydroacridine
- Tacrine
- TACRINE
- tetrahydroaminacrine
Treatment Applications
-
Alzheimer's disease 1View Disease →
DOID:0080348
-
Alzheimer's disease 2View Disease →
DOID:0110035
-
Alzheimer's disease 16View Disease →
DOID:0110036
-
Alzheimer's diseaseView Disease →
DOID:10652
-
Alzheimer's disease 5View Disease →
DOID:0110037
-
Alzheimer's disease 6View Disease →
DOID:0110038
-
Alzheimer's disease 7View Disease →
DOID:0110039
-
Alzheimer's disease 4View Disease →
DOID:0110040
-
Alzheimer's disease 8View Disease →
DOID:0110041
-
Alzheimer's disease 3View Disease →
DOID:0110042
-
Alzheimer's disease 10View Disease →
DOID:0110043
-
Alzheimer's disease 11View Disease →
DOID:0110044
-
Alzheimer's disease 12View Disease →
DOID:0110045
-
Alzheimer's disease 13View Disease →
DOID:0110046
-
Alzheimer's disease 14View Disease →
DOID:0110047
-
Alzheimer's disease 15View Disease →
DOID:0110048
-
Alzheimer's disease 17View Disease →
DOID:0110049
-
Alzheimer's disease 18View Disease →
DOID:0110050
-
Alzheimer's disease 19View Disease →
DOID:0110051
-
Alzheimer's disease 9View Disease →
DOID:0111364
Drug Classification
-
acridinesView Class →
CHEBI:22213
-
aromatic amineView Class →
CHEBI:33860
-
t220399
-
t221063
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 10318
- oboInOwl#hasDbXref
- Wikipedia:Tacrine
- core#notation
- CHEBI:45980
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 10318
- oboInOwl#hasDbXref
- Wikipedia:Tacrine
- oboInOwl#hasAlternativeId
- CHEBI:9389
- oboInOwl#id
- CHEBI:45980
- core#notation
- CHEBI:45980
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_38462
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_187896
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_1289
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_105685
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect12938
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_187896
- owl#someValuesFrom
- t840961
- owl#annotatedSource
- t221401