Discuss This Drug

Fluconazole

CHEBI:CHEBI_46081

Definition

A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Chemical Information

Molecular Formula
C13H12F2N6O
Molecular Mass
306.27080
Charge
0
SMILES
OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F
InChI
InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
InChIKey
RFHAOTPXVQNOHP-UHFFFAOYSA-N

Alternative Names

  • 2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol
  • 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
  • 2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol
  • Biozole
  • Diflucan
  • Elazor
  • fluconazol
  • fluconazole
  • fluconazole
  • fluconazolum
  • Triflucan

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
4450
oboInOwl#hasDbXref
Wikipedia:Fluconazole
core#notation
CHEBI:46081

Additional References

Wikipedia:Fluconazole

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

product_ndc
70771-1063
package_ndc
51686-0006-1
package_marketing_start_date
27-JAN-03
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
dosage_form
INJECTION, SOLUTION
labeler_name
Minsheng Group Shaoxing Pharmaceutical Co., LTD.
application_number
ANDA078764
package_description
2 TABLET in 1 BOTTLE (71335-0686-1)
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
4450
oboInOwl#hasDbXref
Wikipedia:Fluconazole
oboInOwl#hasAlternativeId
CHEBI:5099
oboInOwl#id
CHEBI:46081
brand_name
Fluconazole in Sodium Chloride
brand_name_base
Fluconazole in Sodium Chloride
generic_name
Fluconazole (CIP Process)
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50183
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_35550
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_38584
route
INTRAVENOUS
spl_id
b5e6315d-969a-425f-805b-b29cfd68214a
listing_expiration_date
20241231
marketing_start_date
20030127
rxcui
1721315
manufacturer_name
St Marys Medical Park Pharmacy
unii
8VZV102JFY
spl_set_id
d9e772e9-d916-42ae-8020-89b263236102
active_ingredient_strength
1400 mg/35mL
nui
N0000185504
active_ingredient_name
FLUCONAZOLE
upc
0372789209029
core#notation
CHEBI:46081
pharm_class_epc
Azole Antifungal [EPC]
pharm_class
Cytochrome P450 2C9 Inhibitors [MoA]
pharm_class_cs
Azoles [CS]
pharm_class_moa
Cytochrome P450 2C9 Inhibitors [MoA]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
has_treatment
http://purl.obolibrary.org/obo/DOID_13368
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_112849
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24697
owl#annotatedSource
t221497
owl#someValuesFrom
t2910075