Fluconazole
CHEBI:CHEBI_46081
Definition
A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Chemical Information
- Molecular Formula
- C13H12F2N6O
- Molecular Mass
- 306.27080
- Charge
- 0
- SMILES
- OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F
- InChI
- InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
- InChIKey
- RFHAOTPXVQNOHP-UHFFFAOYSA-N
Alternative Names
- 2-(2,4-difluorophenyl)-1,3-bis-(1H-1,2,4-triazol-1-yl)propan-2-ol
- 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
- 2,4-difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol
- Biozole
- Diflucan
- Elazor
- fluconazol
- fluconazole
- fluconazole
- fluconazolum
- Triflucan
Treatment Applications
-
obsolete rhinocerebral mucormycosisView Disease →
DOID:0050090
-
paracoccidioidomycosisView Disease →
DOID:12662
-
oral candidiasisView Disease →
DOID:14262
Drug Classification
-
conazole antifungal drugView Class →
CHEBI:87071
-
tertiary alcoholView Class →
CHEBI:26878
-
difluorobenzeneView Class →
CHEBI:38582
-
triazole antifungal drugView Class →
CHEBI:87101
-
t220205
-
t220222
-
t220316
-
t220740
-
t221493
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 4450
- oboInOwl#hasDbXref
- Wikipedia:Fluconazole
- core#notation
- CHEBI:46081
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- product_ndc
- 70771-1063
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
- dosage_form
- INJECTION, SOLUTION
- labeler_name
- Minsheng Group Shaoxing Pharmaceutical Co., LTD.
- application_number
- ANDA078764
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 4450
- oboInOwl#hasDbXref
- Wikipedia:Fluconazole
- oboInOwl#hasAlternativeId
- CHEBI:5099
- oboInOwl#id
- CHEBI:46081
- brand_name
- Fluconazole in Sodium Chloride
- brand_name_base
- Fluconazole in Sodium Chloride
- generic_name
- Fluconazole (CIP Process)
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50183
- chebi#has_parent_hydride
- http://purl.obolibrary.org/obo/CHEBI_35550
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_38584
- listing_expiration_date
- 20241231
- marketing_start_date
- 20030127
- spl_id
- 0fe06865-7270-893b-e063-6294a90a04cb
- package_ndc
- 50090-0947-3
- rxcui
- 1721315
- manufacturer_name
- St Marys Medical Park Pharmacy
- unii
- 8VZV102JFY
- spl_set_id
- d9e772e9-d916-42ae-8020-89b263236102
- package_marketing_start_date
- 20190312
- route
- INTRAVENOUS
- has_treatment
- http://purl.obolibrary.org/obo/DOID_13368
- package_description
- 12 BLISTER PACK in 1 CARTON (70518-3092-0) / 1 TABLET in 1 BLISTER PACK
- active_ingredient_strength
- 1400 mg/35mL
- nui
- N0000185504
- active_ingredient_name
- FLUCONAZOLE
- upc
- 0372789209029
- core#notation
- CHEBI:46081
- pharm_class_epc
- Azole Antifungal [EPC]
- pharm_class
- Cytochrome P450 2C9 Inhibitors [MoA]
- pharm_class_cs
- Azoles [CS]
- pharm_class_moa
- Cytochrome P450 2C9 Inhibitors [MoA]
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_112849
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect24697
- owl#annotatedSource
- t221497
- owl#someValuesFrom
- t2910075