Discuss This Drug

Diphenhydramine

CHEBI:CHEBI_4636

Definition

An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.

Chemical Information

Molecular Formula
C17H21NO
Molecular Mass
255.35470
Charge
0
SMILES
CN(C)CCOC(c1ccccc1)c1ccccc1
InChI
InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
InChIKey
ZZVUWRFHKOJYTH-UHFFFAOYSA-N

Alternative Names

  • 2-(benzhydryloxy)-N,N-dimethylethylamine
  • 2-(diphenylmethoxy)-N,N-dimethylethanamine
  • 2-diphenylmethoxy-N,N-demthylethanamine
  • alpha-(2-dimethylaminoethoxy)diphenylmethane
  • beta-dimethylaminoethanol diphenylmethyl ether
  • beta-dimethylaminoethyl benzhydryl ether
  • difenhidramina
  • diphenhydramine
  • diphenhydraminum
  • N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine
  • O-benzhydryldimethylaminoethanol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3498
oboInOwl#hasDbXref
Wikipedia:Diphenhydramine
core#notation
CHEBI:4636

Additional References

Wikipedia:Diphenhydramine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

brand_name
Betr sleep aid
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3498
oboInOwl#hasDbXref
Wikipedia:Diphenhydramine
oboInOwl#id
CHEBI:4636
generic_name
Diphenhydramine Hydrochloride and Phenylephrine Hydrochloride
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723854
brand_name_base
CareOne Nighttime Sleep Aid
product_ndc
63941-916
owl#someValuesFrom
t1116097
labeler_name
YYBA Corporation
marketing_start_date
20051221
application_number
ANDA091526
dosage_form
BAR, CHEWABLE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
Medication
http://purl.obolibrary.org/obo/DOID_0040004
Treatment_Option
http://purl.obolibrary.org/obo/DOID_0040010
Drug_Name
http://purl.obolibrary.org/obo/DOID_0040013
has_treatment
http://purl.obolibrary.org/obo/DOID_8659
spl_id
09f33c6a-b300-4d24-b940-88605ce72651
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24672
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_4604
owl#annotatedSource
t224585
package_ndc
69168-247-24
route
INTRAVENOUS
listing_expiration_date
20241231
package_description
2 BLISTER PACK in 1 CARTON (70677-1128-1) / 12 TABLET, FILM COATED in 1 BLISTER PACK
package_marketing_start_date
20220616
manufacturer_name
YYBA Corporation
spl_set_id
621ba20e-75c5-42fb-9692-7800f764c978
rxcui
1093113
unii
8GTS82S83M
upc
0384324000015
active_ingredient_name
DIPHENHYDRAMINE
active_ingredient_strength
.73 kg/kg
core#notation
CHEBI:4636
nui
N0000175587
brand_name_suffix
Soothing Sleep Nighttime Sleep-Aid
pharm_class
alpha-1 Adrenergic Agonist [EPC]
pharm_class_epc
Histamine-1 Receptor Antagonist [EPC]
pharm_class_moa
Histamine H1 Receptor Antagonists [MoA]
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class