Discuss This Drug

Diphenhydramine

CHEBI:CHEBI_4636

Definition

An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.

Chemical Information

Molecular Formula
C17H21NO
Molecular Mass
255.35470
Charge
0
SMILES
CN(C)CCOC(c1ccccc1)c1ccccc1
InChI
InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
InChIKey
ZZVUWRFHKOJYTH-UHFFFAOYSA-N

Alternative Names

  • 2-(benzhydryloxy)-N,N-dimethylethylamine
  • 2-(diphenylmethoxy)-N,N-dimethylethanamine
  • 2-diphenylmethoxy-N,N-demthylethanamine
  • alpha-(2-dimethylaminoethoxy)diphenylmethane
  • beta-dimethylaminoethanol diphenylmethyl ether
  • beta-dimethylaminoethyl benzhydryl ether
  • difenhidramina
  • diphenhydramine
  • diphenhydraminum
  • N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine
  • O-benzhydryldimethylaminoethanol

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

DRON_00010000
3498
oboInOwl#hasDbXref
Wikipedia:Diphenhydramine
core#notation
CHEBI:4636

Additional References

Wikipedia:Diphenhydramine

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

brand_name_base
Betr sleep aid
brand_name
Rite Aid Extra Strength Itch Stopping
generic_name
Diphenhydramine HCl, Zinc acetate
product_ndc
66715-6406
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3498
oboInOwl#hasDbXref
Wikipedia:Diphenhydramine
oboInOwl#id
CHEBI:4636
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_37955
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
BFO_0000053
http://purl.obolibrary.org/obo/DRON_00723854
dosage_form
BAR, CHEWABLE
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
application_number
ANDA040498
marketing_start_date
20130502
labeler_name
NuCare Pharmaceuticals, Inc.
listing_expiration_date
20241231
spl_id
09f33c6a-b300-4d24-b940-88605ce72651
route
INTRAVENOUS
package_ndc
83324-016-04
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24672
BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_4604
owl#someValuesFrom
t3925026
owl#annotatedSource
t224585
package_description
16 BLISTER PACK in 1 CARTON (55910-916-16) / 1 CAPSULE in 1 BLISTER PACK
package_marketing_start_date
16-FEB-07
Medication
http://purl.obolibrary.org/obo/DOID_0040004
Treatment_Option
http://purl.obolibrary.org/obo/DOID_0040010
Drug_Name
http://purl.obolibrary.org/obo/DOID_0040013
has_treatment
http://purl.obolibrary.org/obo/DOID_8659
rxcui
1093113
unii
8GTS82S83M
spl_set_id
d66ae916-36d3-462a-943e-4ad844dadcaa
manufacturer_name
YYBA Corporation
active_ingredient_name
DIPHENHYDRAMINE
active_ingredient_strength
.73 kg/kg
upc
0384324000015
nui
N0000175587
core#notation
CHEBI:4636
brand_name_suffix
Soothing Sleep Nighttime Sleep-Aid
pharm_class
alpha-1 Adrenergic Agonist [EPC]
pharm_class_epc
Histamine-1 Receptor Antagonist [EPC]
pharm_class_moa
Histamine H1 Receptor Antagonists [MoA]
pharm_class_cs
Anti-Inflammatory Agents, Non-Steroidal [CS]
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class