Dipivefrin
CHEBI:CHEBI_4646
Definition
The dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.
Chemical Information
- Molecular Formula
- C19H29NO5
- Molecular Mass
- 351.43730
- Charge
- 0
- SMILES
- CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1
- InChI
- InChI=1S/C19H29NO5/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6/h8-10,13,20-21H,11H2,1-7H3
- InChIKey
- OCUJLLGVOUDECM-UHFFFAOYSA-N
Alternative Names
- (+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
- 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol
- 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate
- 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate)
- dipivalyl epinephrine
- Dipivefrin
- dipivefrina
- dipivefrine
- Dipivefrine
- dipivefrinum
Treatment Applications
-
ectopia lentis with ectopia of pupilView Disease →
DOID:0111648
-
hypertensive retinopathyView Disease →
DOID:11561
-
regular astigmatismView Disease →
DOID:11781
-
ocular hyperemiaView Disease →
DOID:1248
-
irregular astigmatismView Disease →
DOID:13919
-
ocular hypotensionView Disease →
DOID:790
Drug Classification
-
pivalate esterView Class →
CHEBI:50784
-
ethanolaminesView Class →
CHEBI:23981
-
t223863
-
t224397
-
t224500
-
t224609
-
t224629
-
t224729
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 23410
- oboInOwl#hasDbXref
- Wikipedia:Dipivefrin
- core#notation
- CHEBI:4646
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- rdf-schema#range
- https://w3id.org/def/predibionto#has_drug_109138
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect24761
- chebi#is_conjugate_acid_of
- http://purl.obolibrary.org/obo/CHEBI_73714
- owl#annotatedSource
- t224900
- owl#someValuesFrom
- t567362
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 23410
- oboInOwl#hasDbXref
- Wikipedia:Dipivefrin
- oboInOwl#id
- CHEBI:4646
- core#notation
- CHEBI:4646
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_37886
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#has_functional_parent
- http://purl.obolibrary.org/obo/CHEBI_33568
- chebi#is_conjugate_base_of
- http://purl.obolibrary.org/obo/CHEBI_73714
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class