Discuss This Drug

Ganciclovir

CHEBI:CHEBI_465284

Definition

An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.

Chemical Information

Molecular Formula
C9H13N5O4
Molecular Mass
255.23060
Charge
0
SMILES
Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1
InChI
InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChIKey
IRSCQMHQWWYFCW-UHFFFAOYSA-N

Alternative Names

  • 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol
  • 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one
  • 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one
  • 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol
  • 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one
  • 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone
  • 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one
  • 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine
  • 9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE
  • 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine
  • GA2
  • ganciclovir
  • Ganciclovir
  • ganciclovirum
  • gancyclovir

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
PMID:17539622
DRON_00010000
4678
core#notation
CHEBI:465284

Additional References

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#id
CHEBI:465284
brand_name
GANCICLOVIR
brand_name_base
GANCICLOVIR
generic_name
Ganciclovir Sodium
oboInOwl#hasDbXref
PMID:17539622
product_ndc
12806-6941
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
DRON_00010000
4678
oboInOwl#hasAlternativeId
CHEBI:5273
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_36044
chebi#has_functional_parent
http://purl.obolibrary.org/obo/CHEBI_63635
core#notation
CHEBI:465284
rxcui
1999531
nui
N0000175461
pharm_class_moa
DNA Polymerase Inhibitors [MoA]
pharm_class
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
manufacturer_name
EXELA PHARMA SCIENCES, LLC
active_ingredient_strength
500 mg/.01kg
package_marketing_start_date
20170228
pharm_class_epc
Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor [EPC]
active_ingredient_name
2-AMINO-9-(((1RS)-2-CHLORO-1-(HYDROXYMETHYL)ETHOXY)METHYL)-1,9-DIHYDRO-6H-PURIN-6-ONE
unii
P9G3CKZ4P5
spl_set_id
87afd103-6e64-444f-971d-0e732e9ae995
upc
0363323315016
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
marketing_start_date
19890623
labeler_name
Excella GmbH Co. KG
route
INTRAVENOUS
application_number
ANDA204950
spl_id
a78c687e-d547-4800-bce8-2e4483fb166f
package_ndc
12806-6941-2
package_description
28 kg in 1 DRUM (12806-6941-2)
has_treatment
http://purl.obolibrary.org/obo/DOID_6180
owl#annotatedSource
t224186
owl#someValuesFrom
t2991536
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113467
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24792