Discuss This Drug

Disulfiram

CHEBI:CHEBI_4659

Definition

An organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.

Chemical Information

Molecular Formula
C10H20N2S4
Molecular Mass
296.544
Charge
0
SMILES
S(SC(N(CC)CC)=S)C(N(CC)CC)=S
InChI
InChI=1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
InChIKey
AUZONCFQVSMFAP-UHFFFAOYSA-N

Alternative Names

  • 1,1'-dithiobis(N,N-diethylthioformamide)
  • 1,1',1'',1'''-[disulfanediylbis(carbonothioylnitrilo)]tetraethane
  • Antabuse
  • bis(diethylthiocarbamoyl) disulfide
  • Disulfiram
  • N,N,N',N'-tetraethylthiuram disulfide
  • tetraethylthioperoxydicarbonic diamide
  • tetraethylthiuram disulfide
  • Tetraethylthiuram disulfide
  • tetraethylthiuram disulphide

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:4659
DRON_00010000
3554
oboInOwl#hasDbXref
Wikipedia:Disulfiram

Additional References

Wikipedia:Disulfiram

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

rxcui
197624
product_type
BULK INGREDIENT
listing_expiration_date
20241231
route
ORAL
dosage_form
POWDER
marketing_category
BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING
marketing_start_date
20011116
active_ingredient_strength
1 kg/kg
package_marketing_start_date
16-NOV-01
labeler_name
PolyCarbon Industries, Inc.
manufacturer_name
Chartwell RX, LLC
active_ingredient_name
DISULFIRAM
spl_id
0e98f367-f605-fc02-e063-6394a90ae4f3
package_ndc
51927-0188-0
package_description
1 kg in 1 BOTTLE (51927-0188-0)
application_number
ANDA091681
unii
TR3MLJ1UAI
spl_set_id
d3832a1a-a140-49c1-a7df-134fa81341e3
nui
N0000175679
upc
0347781607302
pharm_class_epc
Aldehyde Dehydrogenase Inhibitor [EPC]
pharm_class
Acetyl Aldehyde Dehydrogenase Inhibitors [MoA]
pharm_class_moa
Acetyl Aldehyde Dehydrogenase Inhibitors [MoA]
core#notation
CHEBI:4659
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
3554
oboInOwl#hasDbXref
Wikipedia:Disulfiram
oboInOwl#id
CHEBI:4659
generic_name
Disulfiram Powdered
brand_name
Disulfiram
brand_name_base
Disulfiram
product_ndc
51927-0188
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50276
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
has_treatment
http://purl.obolibrary.org/obo/DOID_302
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24834
owl#annotatedSource
t224916
owl#someValuesFrom
t906743