Discuss This Drug

docetaxel anhydrous

CHEBI:CHEBI_4672

Definition

A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.

Chemical Information

Molecular Formula
C43H53NO14
Molecular Mass
807.87920
Charge
0
SMILES
[H][C@@]1(C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)[C@]3([H])[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C(=C1C)C2(C)C)OC(C)=O)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1
InChI
InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1
InChIKey
ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Alternative Names

  • 4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
  • Docetaxel
  • Docetaxel anhydrous
  • N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
  • N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
  • TXL

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

oboInOwl#hasDbXref
Wikipedia:Docetaxel
core#notation
CHEBI:4672

Additional References

Wikipedia:Docetaxel

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

BFO_0000051
http://purl.obolibrary.org/obo/CHEBI_59809
rdf-schema#domain
https://w3id.org/def/predibionto#has_side_effect24868
owl#annotatedSource
t224764
owl#someValuesFrom
t255816
oboInOwl#hasOBONamespace
chebi_ontology
oboInOwl#hasDbXref
Wikipedia:Docetaxel
oboInOwl#id
CHEBI:4672
brand_name
DOCETAXEL
brand_name_base
DOCETAXEL
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
listing_expiration_date
20241231
dosage_form
INJECTION, SOLUTION
marketing_start_date
20121120
route
INTRAVENOUS
labeler_name
Phyton Biotech LLC
generic_name
Docetaxel Anhydrous
application_number
ANDA210848
product_ndc
0409-2026
spl_id
2791bcee-363b-475d-8873-5985bc3b1de6
package_ndc
0409-2026-01
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_38068
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
chebi#has_parent_hydride
http://purl.obolibrary.org/obo/CHEBI_36064
core#notation
CHEBI:4672
rxcui
1860619
package_marketing_start_date
20-NOV-12
active_ingredient_strength
100 kg/100kg
nui
N0000175592
pharm_class_epc
Microtubule Inhibitor [EPC]
pharm_class
Microtubule Inhibition [PE]
pharm_class_pe
Microtubule Inhibition [PE]
manufacturer_name
Hospira, Inc.
active_ingredient_name
DOCETAXEL ANHYDROUS
unii
699121PHCA
package_description
1 VIAL, SINGLE-DOSE in 1 CARTON (0409-2026-01) / 2 mL in 1 VIAL, SINGLE-DOSE
spl_set_id
2992d633-08fa-44f3-b14d-41700f24686b
upc
0372078040081
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class