dofetilide
CHEBI:CHEBI_4681
Definition
A tertiary amino compound that is N-ethyl-N-methylethanamine substituted by a 4-[(methylsulfonyl)amino]phenoxy and a 4-[(methylsulfonyl)amino]phenyl group at the terminal carbon atoms respectively. It is used as an anti-arrhythmia drug.
Chemical Information
- Molecular Formula
- C19H27N3O5S2
- Molecular Mass
- 441.56500
- Charge
- 0
- SMILES
- CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1
- InChI
- InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
- InChIKey
- IXTMWRCNAAVVAI-UHFFFAOYSA-N
Alternative Names
- beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide
- dofetilida
- dofetilide
- Dofetilide
- dofetilidum
- N-(4-{2-[methyl(2-{4-[(methylsulfonyl)amino]phenoxy}ethyl)amino]ethyl}phenyl)methanesulfonamide
- Tikosyn
Drug Classification
-
sulfonamideView Class →
CHEBI:35358
-
aromatic etherView Class →
CHEBI:35618
-
tertiary amino compoundView Class →
CHEBI:50996
-
t223647
-
t224558
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- DRON_00010000
- 49247
- oboInOwl#hasDbXref
- Wikipedia:Dofetilide
- core#notation
- CHEBI:4681
Additional References
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- route
- ORAL
- package_ndc
- 14096-192-01
- package_description
- 5 kg in 1 DRUM (14096-192-01)
- spl_id
- a8505d9b-3ae3-4aec-b033-4ac8ffd85a9d
- product_type
- BULK INGREDIENT
- marketing_category
- BULK INGREDIENT
- listing_expiration_date
- 20241231
- dosage_form
- CAPSULE
- marketing_start_date
- 20160607
- labeler_name
- The Janz Corporation
- application_number
- ANDA210740
- product_ndc
- 16729-492
- oboInOwl#hasOBONamespace
- chebi_ontology
- DRON_00010000
- 49247
- oboInOwl#hasDbXref
- Wikipedia:Dofetilide
- oboInOwl#id
- CHEBI:4681
- generic_name
- Dofetilide 0.5mg
- brand_name
- Dofetilide 0.5mg
- brand_name_base
- Dofetilide 0.5mg
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_50509
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- package_marketing_start_date
- 08-DEC-23
- manufacturer_name
- The Janz Corporation
- core#notation
- CHEBI:4681
- rxcui
- 285016
- active_ingredient_strength
- 50 kg/50kg
- nui
- N0000175426
- pharm_class_epc
- Antiarrhythmic [EPC]
- pharm_class
- Antiarrhythmic [EPC]
- active_ingredient_name
- DOFETILIDE
- unii
- R4Z9X1N2ND
- spl_set_id
- a10633a6-4518-4a87-a880-faaa33bdbec6
- upc
- 0370010026063
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- has_treatment
- http://purl.obolibrary.org/obo/DOID_0060339
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect24899
- owl#annotatedSource
- t224933
- owl#someValuesFrom
- t823698