Discuss This Drug

Doxercalciferol

CHEBI:CHEBI_4712

Definition

A hydroxy seco-steroid and synthetic vitamin D2 analogue that undergoes metabolic activation in vivo to form 1alpha,25-dihydroxyvitamin D2 (1alpha,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH; a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease.

Chemical Information

Molecular Formula
C28H44O2
Molecular Mass
412.649
Charge
0
SMILES
C1[C@]2([C@](/C(=C/C=C/3\C([C@H](C[C@@H](C3)O)O)=C)/CC1)(CC[C@@]2([C@H](C)/C=C/[C@@H](C(C)C)C)[H])[H])C
InChI
InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1
InChIKey
HKXBNHCUPKIYDM-CGMHZMFXSA-N

Alternative Names

  • (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol
  • 1alpha-hydroxyergocalciferol
  • 1alpha-hydroxyvitamin D2
  • doxercalciferol
  • doxercalciferolum
  • Hectorol

Treatment Applications

Drug Classification

Important Medical Information

⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.

  • Always consult with a healthcare professional before starting, stopping, or modifying any medication.
  • Side effects may vary and this list may not be comprehensive.
  • Drug interactions may occur with other medications.

Additional Identifiers

core#notation
CHEBI:4712
DRON_00010000
11516
oboInOwl#hasDbXref
Wikipedia:Doxercalciferol

Additional References

Wikipedia:Doxercalciferol

🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.

Additional Attributes

core#notation
CHEBI:4712
rxcui
1790220
manufacturer_name
Alembic Pharmaceuticals Inc.
package_marketing_start_date
20130830
active_ingredient_strength
2.5 ug/1
active_ingredient_name
DOXERCALCIFEROL
nui
N0000175907
pharm_class
Vitamin D2 Analog [EPC]
pharm_class_cs
Ergocalciferols [CS]
pharm_class_epc
Vitamin D2 Analog [EPC]
unii
3DIZ9LF5Y9
spl_set_id
b00fcf3f-c576-4121-b305-05bcbdd3525e
upc
0368180718529
package_description
30 CAPSULE in 1 BOTTLE (62135-451-30)
22-rdf-syntax-ns#type
http://www.w3.org/2002/07/owl#Class
oboInOwl#hasOBONamespace
chebi_ontology
DRON_00010000
11516
oboInOwl#hasDbXref
Wikipedia:Doxercalciferol
oboInOwl#id
CHEBI:4712
generic_name
DOXERCALCIFEROL
brand_name
DOXERCALCIFEROL
brand_name_base
DOXERCALCIFEROL
product_type
BULK INGREDIENT
marketing_category
BULK INGREDIENT
dosage_form
CAPSULE, LIQUID FILLED
labeler_name
Cerbios-Pharma SA
product_ndc
70121-1392
application_number
ANDA210801
RO_0000087
http://purl.obolibrary.org/obo/CHEBI_50188
oboInOwl#inSubset
http://purl.obolibrary.org/obo/chebi#3_STAR
listing_expiration_date
20241231
route
INTRAVENOUS
marketing_start_date
20130830
spl_id
c8475157-5c34-442b-ac41-c3ce4346ff96
package_ndc
70121-1392-6
rdf-schema#range
https://w3id.org/def/predibionto#has_drug_113900
owl#annotatedSource
t224792
owl#someValuesFrom
t2997193