Imipenem
CHEBI:CHEBI_471744
Definition
A broad-spectrum, intravenous beta-lactam antibiotic of the carbapenem subgroup.
Chemical Information
- Molecular Formula
- C12H17N3O4S
- Molecular Mass
- 299.34720
- Charge
- 0
- SMILES
- [H]C(=N)NCCSC1=C(N2C(=O)[C@]([H])([C@@H](C)O)[C@@]2([H])C1)C(O)=O
- InChI
- InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1
- InChIKey
- ZSKVGTPCRGIANV-ZXFLCMHBSA-N
Alternative Names
- (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
- (5R,6S)-3-(2-Formimidoylamino-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- (5R,6S)-6-((R)-1-Hydroxyethyl)-3-(2-(iminomethylamino)ethylthio)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carbonsaeure
- (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- Imipenem
- Imipenem anhydrous
- imipenemum
- N-formimidoyl thienamycin
- N-formimidoylthienamycin
Drug Classification
-
beta-lactam antibiotic allergenView Class →
CHEBI:88225
-
carbapenemsView Class →
CHEBI:46633
-
t224123
-
t224538
Important Medical Information
⚕️ This information is sourced from ChEBI (Chemical Entities of Biological Interest) database and is intended for educational purposes only.
- Always consult with a healthcare professional before starting, stopping, or modifying any medication.
- Side effects may vary and this list may not be comprehensive.
- Drug interactions may occur with other medications.
Additional Identifiers
- core#notation
- CHEBI:471744
- oboInOwl#hasDbXref
- Wikipedia:Imipenem
- DRON_00010000
- 5690
Additional References
Wikipedia:Imipenem
🔍 Click on any linked disease name to learn more about the conditions this medication is used to treat, or explore related drug classifications for more information about similar medications.
Additional Attributes
- core#notation
- CHEBI:471744
- rxcui
- 2184147
- active_ingredient_strength
- 250 mg/20mL
- route
- INTRAVENOUS
- pharm_class_epc
- Renal Dehydropeptidase Inhibitor [EPC]
- pharm_class
- Renal Dehydropeptidase Inhibitor [EPC]
- pharm_class_moa
- Dipeptidase Inhibitors [MoA]
- package_marketing_start_date
- 19851126
- manufacturer_name
- WG Critical Care, LLC
- active_ingredient_name
- IMIPENEM
- package_ndc
- 52946-0930-0
- package_description
- 20 kg in 1 BOX (52946-0930-0)
- pharm_class_cs
- Carbapenems [CS]
- nui
- N0000175496
- unii
- 1OQF7TT3PF
- spl_set_id
- 46f54df9-5afe-430c-aa19-0d84c2044b0b
- upc
- 0344567705016
- brand_name_suffix
- IV
- spl_id
- 0912f897-b3b8-458f-a541-7bd9c58c12c5
- 22-rdf-syntax-ns#type
- http://www.w3.org/2002/07/owl#Class
- oboInOwl#hasOBONamespace
- chebi_ontology
- oboInOwl#hasDbXref
- Wikipedia:Imipenem
- DRON_00010000
- 5690
- oboInOwl#id
- CHEBI:471744
- oboInOwl#hasAlternativeId
- CHEBI:5879
- generic_name
- imipenem anhydrous, cilastatin, and relebactam anhydrous
- product_type
- BULK INGREDIENT
- marketing_category
- EXPORT ONLY
- listing_expiration_date
- 20251231
- dosage_form
- INJECTION, POWDER, FOR SOLUTION
- marketing_start_date
- 19851126
- labeler_name
- Merck Sharp & Dohme Corp.
- product_ndc
- 52946-0930
- brand_name
- RECARBRIO
- brand_name_base
- RECARBRIO
- application_number
- ANDA207594
- RO_0000087
- http://purl.obolibrary.org/obo/CHEBI_36047
- oboInOwl#inSubset
- http://purl.obolibrary.org/obo/chebi#3_STAR
- chebi#is_tautomer_of
- http://purl.obolibrary.org/obo/CHEBI_190509
- rdf-schema#domain
- https://w3id.org/def/predibionto#has_side_effect13380
- has_treatment
- http://purl.obolibrary.org/obo/DOID_10531
- owl#annotatedSource
- t224485
- owl#someValuesFrom
- t145050